Benjamin Fook Lun Lai
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Explore the profile of Benjamin Fook Lun Lai including associated specialties, affiliations and a list of published articles.
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8
Citations
228
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Recent Articles
1.
Mohammadi M, Okhovatian S, Savoji H, Campbell S, Lai B, Wu J, et al.
Adv Biol (Weinh)
. 2022 Jul;
6(11):e2101165.
PMID: 35798316
Despite current efforts in organ-on-chip engineering to construct miniature cardiac models, they often lack some physiological aspects of the heart, including fiber orientation. This motivates the development of bioartificial left...
2.
Lu R, Lai B, Rafatian N, Gustafson D, Campbell S, Banerjee A, et al.
Lab Chip
. 2022 Feb;
22(6):1171-1186.
PMID: 35142777
Coronavirus disease 2019 (COVID-19) was primarily identified as a novel disease causing acute respiratory syndrome. However, as the pandemic progressed various cases of secondary organ infection and damage by severe...
3.
Wang E, Kuzmanov U, Smith J, Dou W, Rafatian N, Lai B, et al.
J Mol Cell Cardiol
. 2021 Jul;
160:97-110.
PMID: 34216608
Angiotensin II (Ang II) presents a critical mediator in various pathological conditions such as non-genetic cardiomyopathy. Osmotic pump infusion in rodents is a commonly used approach to model cardiomyopathy associated...
4.
Lai B, Lu R, Davenport Huyer L, Kakinoki S, Yazbeck J, Wang E, et al.
Nat Protoc
. 2021 Apr;
16(4):2158-2189.
PMID: 33790475
Owing to their high spatiotemporal precision and adaptability to different host cells, organ-on-a-chip systems are showing great promise in drug discovery, developmental biology studies and disease modeling. However, many current...
5.
Savoji H, Davenport Huyer L, Mohammadi M, Lai B, Rafatian N, Bannerman D, et al.
ACS Biomater Sci Eng
. 2021 Jan;
6(3):1333-1343.
PMID: 33455372
Bioelastomers have been extensively used in tissue engineering applications because of favorable mechanical stability, tunable properties, and chemical versatility. As these materials generally possess low elastic modulus and relatively long...
6.
Wang E, Rafatian N, Zhao Y, Lee A, Lai B, Lu R, et al.
ACS Cent Sci
. 2019 Aug;
5(7):1146-1158.
PMID: 31403068
Myocardial fibrosis is a severe global health problem due to its prevalence in all forms of cardiac diseases and direct role in causing heart failure. The discovery of efficient antifibrotic...
7.
Zhang B, Lai B, Xie R, Davenport Huyer L, Montgomery M, Radisic M
Nat Protoc
. 2018 Aug;
13(8):1793-1813.
PMID: 30072724
Microengineered biomimetic systems for organ-on-a-chip or tissue engineering purposes often fail as a result of an inability to recapitulate the in vivo environment, specifically the presence of a well-defined vascular...
8.
Conant G, Lai B, Lu R, Korolj A, Wang E, Radisic M
Stem Cell Rev Rep
. 2017 Apr;
13(3):335-346.
PMID: 28429185
Drug discovery and development continues to be a challenge to the pharmaceutical industry despite great advances in cell and molecular biology that allow for the design of better targeted therapeutics....