Benjamin E Steinberg
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Explore the profile of Benjamin E Steinberg including associated specialties, affiliations and a list of published articles.
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54
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Recent Articles
1.
Caracci B, Pehora C, Benson L, Steinberg B, Goldenberg N, Taylor K
J Cardiothorac Vasc Anesth
. 2024 Aug;
38(10):2356-2361.
PMID: 39095209
Objectives: Pulmonary arterial hypertension (PAH) is a devastating complication of pediatric congenital heart disease (CHD). A recent study has identified the protein high mobility group box-1 (HMGB1) as a diagnostic...
2.
David L, Borges J, Hollingsworth L, Volchuk A, Jansen I, Garlick E, et al.
Cell
. 2024 Apr;
187(9):2224-2235.e16.
PMID: 38614101
The membrane protein NINJ1 mediates plasma membrane rupture in pyroptosis and other lytic cell death pathways. Here, we report the cryo-EM structure of a NINJ1 oligomer segmented from NINJ1 rings....
3.
Chin K, Jiang H, Steinberg B, Goldenberg N, Desjardins J, Kabir G, et al.
J Appl Physiol (1985)
. 2024 Feb;
136(5):1245-1259.
PMID: 38385183
Anemia and renal failure are independent risk factors for perioperative stroke, prompting us to assess the combined impact of acute hemodilutional anemia and bilateral nephrectomy (2Nx) on microvascular brain Po...
4.
Wang D, Ju L, Pinguelo A, Kaneshwaran K, Haffey S, Lecker I, et al.
Transl Res
. 2023 Dec;
267:39-53.
PMID: 38042478
General anesthetic drugs cause cognitive deficits that persist after the drugs have been eliminated. Astrocytes may contribute to such cognition-impairing effects through the release of one or more paracrine factors...
5.
Siddiqui A, Faraoni D, Williams R, Eytan D, Levin D, Mazwi M, et al.
Paediatr Anaesth
. 2023 Aug;
33(11):938-945.
PMID: 37555370
Background: Liver transplantation is the life-saving treatment for many end-stage pediatric liver diseases. The perioperative course, including surgical and anesthetic factors, have an important influence on the trajectory of this...
6.
Kayagaki N, Stowe I, Alegre K, Deshpande I, Wu S, Lin Z, et al.
Nature
. 2023 May;
618(7967):1072-1077.
PMID: 37196676
Plasma membrane rupture (PMR) in dying cells undergoing pyroptosis or apoptosis requires the cell-surface protein NINJ1. PMR releases pro-inflammatory cytoplasmic molecules, collectively called damage-associated molecular patterns (DAMPs), that activate immune...
7.
Hirata Y, Cai R, Volchuk A, Steinberg B, Saito Y, Matsuzawa A, et al.
Curr Biol
. 2023 Mar;
33(7):1282-1294.e5.
PMID: 36898371
The ongoing metabolic and microbicidal pathways that support and protect cellular life generate potentially damaging reactive oxygen species (ROS). To counteract damage, cells express peroxidases, which are antioxidant enzymes that...
8.
Halievski K, Sengar A, Hicks J, Haight J, Salter M, Steinberg B
Mol Pain
. 2022 Feb;
18:17448069221076634.
PMID: 35174761
T lymphocytes are increasingly implicated in pain signaling. A subset of T lymphocytes, termed TChAT, express the rate-limiting enzyme for acetylcholine (ACh) production, choline acetyltransferase (ChAT), and mediate numerous physiological...
9.
Foley A, Steinberg B, Goldenberg N
Front Med (Lausanne)
. 2022 Jan;
8:826557.
PMID: 35096915
Inflammasomes are multi-protein complexes that sense both infectious and sterile inflammatory stimuli, launching a cascade of responses to propagate danger signaling throughout an affected tissue. Recent studies have implicated inflammasome...
10.
Sun N, Steinberg B, Faraoni D, Isaac L
Can J Anaesth
. 2021 Dec;
69(8):1025-1032.
PMID: 34904210
Purpose: Legitimate opioid prescriptions can increase the risk of misuse, addiction, and overdose of opioids in children and adolescents. This study aimed to describe the prescribing patterns of discharge opioid...