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Benjamin Dannenmann

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Articles 21
Citations 149
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Recent Articles
1.
Nasri M, Dannenmann B, Doll L, Findik B, Bernhard F, Kandabarau S, et al.
Mol Ther . 2024 Dec; PMID: 39653038
Severe congenital neutropenia (CN) patients require life-long treatment with recombinant human granulocyte colony-stimulating factor (rhG-CSF), but some show no response. We sought to establish a therapy for CN that targets...
2.
Borbaran Bravo N, Deordieva E, Doll L, ElGamacy M, Dannenmann B, Azevedo J, et al.
Blood . 2024 Dec; PMID: 39642330
We have identified a new inherited bone marrow (BM) failure syndrome with severe congenital neutropenia (CN) caused by autosomal recessive mutations in the coatomer protein complex I (COPI) subunit zeta...
3.
Ritter M, Nasri M, Dannenmann B, Mir P, Secker B, Amend D, et al.
CRISPR J . 2024 Oct; 7(5):258-271. PMID: 39436283
Safety considerations for gene therapies of inherited preleukemia syndromes, including severe congenital neutropenia (CN), are paramount. We compared several strategies for CRISPR/Cas9 gene editing of autosomal-dominant mutations in CD34 cells...
4.
Nasri M, Ritter M, Mir P, Dannenmann B, Kaufmann M, Arreba-Tutusaus P, et al.
Mol Ther . 2024 Apr; 32(6):1628-1642. PMID: 38556793
Severe congenital neutropenia (CN) is an inherited pre-leukemia bone marrow failure syndrome commonly caused by autosomal-dominant ELANE mutations (ELANE-CN). ELANE-CN patients are treated with daily injections of recombinant human granulocyte...
5.
Xu Y, Nasri M, Dannenmann B, Mir P, Zahabi A, Welte K, et al.
Stem Cell Res Ther . 2023 Oct; 14(1):299. PMID: 37858174
No abstract available.
6.
Zeidler A, Borbaran-Bravo N, Dannenmann B, Ritter M, Nasri M, Klimiankou M, et al.
Haematologica . 2023 Oct; 109(5):1393-1402. PMID: 37855057
Mutations in the ELANE gene, encoding the neutrophil elastase (NE) protein, are responsible for most cyclic neutropenia (CyN) cases and approximately 25% of congenital neutropenia (CN) cases. In CN and...
7.
Dannenmann B, Klimiankou M, Oswald B, Solovyeva A, Mardan J, Nasri M, et al.
Cell Stem Cell . 2023 Sep; 30(9):1282. PMID: 37683606
No abstract available.
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Dannenmann B, Skokowa J
STAR Protoc . 2022 May; 3(2):101400. PMID: 35600931
Severe congenital neutropenia (CN) is a pre-leukemic bone marrow failure syndrome that can progress to acute myeloid leukemia (CN/AML). Patient material to study leukemogenesis, especially hematopoietic progenitor cells (HPCs) is...
10.
Dannenmann B, Klimiankou M, Oswald B, Solovyeva A, Mardan J, Nasri M, et al.
Cell Stem Cell . 2021 Apr; 28(5):906-922.e6. PMID: 33894142
Severe congenital neutropenia (CN) is a pre-leukemic bone marrow failure syndrome that can evolve to acute myeloid leukemia (AML). Mutations in CSF3R and RUNX1 are frequently observed in CN patients,...