Benjamin B Kaufmann
Overview
Explore the profile of Benjamin B Kaufmann including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
474
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Recent Articles
1.
Grant S, Kaufmann B, Chand N, Haseley N, Hung D
Proc Natl Acad Sci U S A
. 2012 Jul;
109(30):12147-52.
PMID: 22778419
During Mycobacterium tuberculosis infection, a population of bacteria likely becomes refractory to antibiotic killing in the absence of genotypic resistance, making treatment challenging. We describe an in vitro model capable...
2.
Barczak A, Gomez J, Kaufmann B, Hinson E, Cosimi L, Borowsky M, et al.
Proc Natl Acad Sci U S A
. 2012 Apr;
109(16):6217-22.
PMID: 22474362
With rising rates of drug-resistant infections, there is a need for diagnostic methods that rapidly can detect the presence of pathogens and reveal their susceptibility to antibiotics. Here we propose...
3.
Kaufmann B, Hung D
Mol Cell
. 2010 Feb;
37(3):297-8.
PMID: 20159549
In this issue of Molecular Cell, Kohanski et al. (2010) demonstrate that even subinhibitory concentrations of bactericidal antibiotics result in the generation of reactive oxygen species, leading to an increase...
4.
Kaufmann B, Yang Q, Mettetal J, van Oudenaarden A
PLoS Biol
. 2007 Sep;
5(9):e239.
PMID: 17803359
The partitioning and subsequent inheritance of cellular factors like proteins and RNAs is a ubiquitous feature of cell division. However, direct quantitative measures of how such nongenetic inheritance affects subsequent...
5.
Kaufmann B, van Oudenaarden A
Curr Opin Genet Dev
. 2007 Feb;
17(2):107-12.
PMID: 17317149
Protein production involves a series of stochastic chemical steps. One consequence of this fact is that the copy number of any given protein varies substantially from cell to cell, even...
6.
Becskei A, Kaufmann B, van Oudenaarden A
Nat Genet
. 2005 Aug;
37(9):937-44.
PMID: 16086016
The presence of low-copy-number regulators and switch-like signal propagation in regulatory networks are expected to increase noise in cellular processes. We developed a noise amplifier that detects fluctuations in the...