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Benjamin A Fontaine

Explore the profile of Benjamin A Fontaine including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 562
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Recent Articles
1.
Funke M, Knudsen L, Lagares D, Ebener S, Probst C, Fontaine B, et al.
Am J Respir Cell Mol Biol . 2016 Apr; 55(1):105-16. PMID: 27082727
Lysophosphatidic acid (LPA) signaling through one of its receptors, LPA1, contributes to both the development and the pathological remodeling after injury of many organs. Because we found previously that LPA-LPA1...
2.
Black K, Berdyshev E, Bain G, Castelino F, Shea B, Probst C, et al.
FASEB J . 2016 Mar; 30(6):2435-50. PMID: 27006447
Lysophosphatidic acid (LPA) is an important mediator of pulmonary fibrosis. In blood and multiple tumor types, autotaxin produces LPA from lysophosphatidylcholine (LPC) via lysophospholipase D activity, but alternative enzymatic pathways...
3.
Tata P, Pardo-Saganta A, Prabhu M, Vinarsky V, Law B, Fontaine B, et al.
Am J Respir Cell Mol Biol . 2013 Jul; 49(6):1048-56. PMID: 23848320
Tissue-specific transgene expression using tetracycline (tet)-regulated promoter/operator elements has been used to revolutionize our understanding of cellular and molecular processes. However, because most tet-regulated mouse strains use promoters of genes...
4.
Lagares D, Busnadiego O, Garcia-Fernandez R, Kapoor M, Liu S, Carter D, et al.
Arthritis Rheum . 2012 Apr; 64(5):1653-64. PMID: 22492165
Objective: Enhanced adhesive signaling, including activation of focal adhesion kinase (FAK), is a hallmark of fibroblasts from lung fibrosis patients, and FAK has therefore been hypothesized to be a key...
5.
Bosco D, Morfini G, Karabacak N, Song Y, Gros-Louis F, Pasinelli P, et al.
Nat Neurosci . 2010 Oct; 13(11):1396-403. PMID: 20953194
Many mutations confer one or more toxic function(s) on copper/zinc superoxide dismutase 1 (SOD1) that impair motor neuron viability and cause familial amyotrophic lateral sclerosis (FALS). Using a conformation-specific antibody...
6.
Shea B, Brooks S, Fontaine B, Chun J, Luster A, Tager A
Am J Respir Cell Mol Biol . 2010 Jan; 43(6):662-73. PMID: 20081052
Sphingosine 1-phosphate (S1P) is a key endogenous regulator of the response to lung injury, maintaining endothelial barrier integrity through interaction with one of its receptors, S1P(1). The short-term administration of...