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Benedikt M Beckmann

Explore the profile of Benedikt M Beckmann including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 1978
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Recent Articles
11.
Kramer K, Sachsenberg T, Beckmann B, Qamar S, Boon K, Hentze M, et al.
Nat Methods . 2014 Sep; 11(10):1064-70. PMID: 25173706
RNA-protein complexes play pivotal roles in many central biological processes. Although methods based on high-throughput sequencing have advanced our ability to identify the specific RNAs bound by a particular protein,...
12.
Lechner M, Nickel A, Wehner S, Riege K, Wieseke N, Beckmann B, et al.
BMC Genomics . 2014 Jun; 15:522. PMID: 24965762
Background: The Aquificales are a diverse group of thermophilic bacteria that thrive in terrestrial and marine hydrothermal environments. They can be divided into the families Aquificaceae, Desulfurobacteriaceae and Hydrogenothermaceae. Although...
13.
Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann B, Strein C, et al.
Cell . 2012 Jun; 149(6):1393-406. PMID: 22658674
RNA-binding proteins (RBPs) determine RNA fate from synthesis to decay. Employing two complementary protocols for covalent UV crosslinking of RBPs to RNA, we describe a systematic, unbiased, and comprehensive approach,...
14.
Beckmann B, Hoch P, Marz M, Willkomm D, Salas M, Hartmann R
EMBO J . 2012 Feb; 31(7):1727-38. PMID: 22333917
Bacillus subtilis 6S-1 RNA binds to the housekeeping RNA polymerase (σ(A)-RNAP) and directs transcription of short 'product' RNAs (pRNAs). Here, we demonstrate that once newly synthesized pRNAs form a sufficiently...
15.
Beckmann B, Burenina O, Hoch P, Kubareva E, Sharma C, Hartmann R
RNA Biol . 2011 Sep; 8(5):839-49. PMID: 21881410
By differential high-throughput RNA sequencing (dRNA-seq) we have identified "product RNAs" (pRNAs) as short as 8-12 nucleotides that are synthesized by Bacillus subtilis RNA polymerase (RNAP) in vivo using the...
16.
Merkel O, Beyerle A, Beckmann B, Zheng M, Hartmann R, Stoger T, et al.
Biomaterials . 2010 Dec; 32(9):2388-98. PMID: 21183213
Since off-target effects in non-viral siRNA delivery are quite common but not well understood, in this study various polymer-related effects observed in transfection studies were described and their mechanisms of...
17.
Beckmann B, Grunweller A, Weber M, Hartmann R
Nucleic Acids Res . 2010 May; 38(14):e147. PMID: 20504856
Here we describe a northern blot procedure that allows the detection of endogenous RNAs as small as approximately 14 nt in total RNA extracts from bacteria. RNAs that small and...
18.
Cymerman I, Chung I, Beckmann B, Bujnicki J, Meiss G
Nucleic Acids Res . 2008 Jan; 36(4):1369-79. PMID: 18187503
Evolutionary conserved mitochondrial nucleases are involved in programmed cell death and normal cell proliferation in lower and higher eukaryotes. The endo/exonuclease Nuc1p, also termed 'yeast Endonuclease G (EndoG)', is a...