Benedikt L Proffen
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Explore the profile of Benedikt L Proffen including associated specialties, affiliations and a list of published articles.
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43
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747
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Recent Articles
1.
Donnenfield J, Fleming B, Proffen B, Podury A, Murray M
Osteoarthritis Cartilage
. 2023 Sep;
31(12):1554-1566.
PMID: 37742942
Objective: There is no disease-modifying treatment for posttraumatic osteoarthritis (PTOA). This may be partly due to an incomplete understanding of synovitis, which has been causally linked to PTOA progression. The...
2.
Donnenfield J, Proffen B, Fleming B, Murray M
Bioengineering (Basel)
. 2023 May;
10(5).
PMID: 37237597
The relationship between cartilage and synovium is a rapidly growing area of osteoarthritis research. However, to the best of our knowledge, the relationships in gene expression between these two tissues...
3.
Donnenfield J, Karamchedu N, Proffen B, Molino J, Fleming B, Murray M
PLoS One
. 2023 May;
18(5):e0284777.
PMID: 37134114
To determine the transcriptomic changes seen in early- to mid-stage posttraumatic osteoarthritis (PTOA) development, 72 Yucatan minipigs underwent transection of the anterior cruciate ligament. Subjects were randomized to no further...
4.
Flannery S, Beveridge J, Proffen B, Walsh E, Kramer D, Murray M, et al.
Sci Rep
. 2023 Mar;
13(1):3524.
PMID: 36864112
Non-invasive methods to document healing anterior cruciate ligament (ACL) structural properties could potentially identify patients at risk for revision surgery. The objective was to evaluate machine learning models to predict...
5.
Barnes D, Badger G, Yen Y, Micheli L, Kramer D, Fadale P, et al.
Am J Sports Med
. 2023 Jan;
51(2):413-421.
PMID: 36645042
Background: Quantitative magnetic resonance imaging (qMRI) methods were developed to establish the integrity of healing anterior cruciate ligaments (ACLs) and grafts. Whether qMRI variables predict risk of reinjury is unknown....
6.
Parola L, Pinette M, Proffen B, Sant N, Karamchedu N, Costa M, et al.
PLoS One
. 2022 Nov;
17(11):e0278338.
PMID: 36449506
The study objective was to determine if intraarticular injections of an extracellular matrix (ECM) powder and blood composite (ECM-B) would have a significant impact on post-operative gait parameters without eliciting...
7.
Pinette M, Molino J, Proffen B, Murray M, Fleming B
Am J Sports Med
. 2022 Jun;
50(9):2417-2423.
PMID: 35722806
Background: Posttraumatic osteoarthritis (PTOA) is a common sequela of anterior cruciate ligament (ACL) injury, even when surgical treatment is selected. The effect of patient sex on cartilage health after ACL...
8.
Donnenfield J, Karamchedu N, Proffen B, Molino J, Murray M, Fleming B
PLoS One
. 2022 Jun;
17(6):e0268198.
PMID: 35675298
The inflammatory response to joint injury has been thought to play a key role in the development of osteoarthritis. In this preclinical study, we hypothesized that synovial fluid presence of...
9.
Donnenfield J, Karamchedu N, Fleming B, Molino J, Proffen B, Murray M
Am J Transl Res
. 2022 Apr;
14(3):1640-1651.
PMID: 35422952
The primary source of synovial fluid inflammatory mediators is currently unknown and may include different tissues comprising the joint, including the synovium and articular cartilage. Prior work in a porcine...
10.
Kiapour A, Flannery S, Murray M, Miller P, Proffen B, Sant N, et al.
Am J Sports Med
. 2021 Oct;
49(14):3833-3841.
PMID: 34668789
Background: Magnetic resonance-based measurements of signal intensity have been used to track healing of surgically treated anterior cruciate ligaments (ACLs). However, it is unknown how the signal intensity values in...