Benedikt L Proffen
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Explore the profile of Benedikt L Proffen including associated specialties, affiliations and a list of published articles.
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43
Citations
747
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Recent Articles
11.
Sant N, Proffen B, Murray M
J Biomater Appl
. 2021 Oct;
36(6):1011-1018.
PMID: 34607497
Sterilization of medical devices is commonly performed using radiation methods. However, collagen materials can be damaged when using standard radiation doses (25 kGy). Small increases of radiation dose can allow...
12.
Costa M, Murray M, Sieker J, Karamchedu N, Proffen B, Fleming B
PLoS One
. 2021 Aug;
16(8):e0256765.
PMID: 34437631
Anterior cruciate ligament injuries result in posttraumatic osteoarthritis in the medial compartment of the knee, even after surgical treatment. How the chondrocyte distribution within the articular cartilage changes early in...
13.
Karamchedu N, Fleming B, Donnenfield J, Proffen B, Costa M, Molino J, et al.
Am J Transl Res
. 2021 Aug;
13(7):7667-7676.
PMID: 34377243
The roles that cytokines and matrix metalloproteinases play in the onset and progression of posttraumatic osteoarthritis (PTOA) remain a topic of debate. The study objective was to evaluate the concentrations...
14.
Karamchedu N, Fleming B, Proffen B, Sant N, Portilla G, Parola L, et al.
J Orthop Res
. 2021 Apr;
40(3):573-583.
PMID: 33913543
The objective was to determine if an intra-articular injection of an extracellular matrix (ECM) powder and blood composite (ECM-B) after anterior cruciate ligament (ACL) injury would have a mitigating effect...
15.
Karamchedu N, Murray M, Sieker J, Proffen B, Portilla G, Costa M, et al.
Am J Sports Med
. 2021 Feb;
49(3):667-674.
PMID: 33534613
Background: The extent of posttraumatic osteoarthritis (PTOA) in the porcine anterior cruciate ligament (ACL) transection model is dependent on the surgical treatment selected. In a previous study, animals treated with...
16.
Freiberger C, Kiapour A, Liu S, Henderson R, Barnett S, Sant N, et al.
Orthop J Sports Med
. 2020 Jul;
8(7):2325967120927655.
PMID: 32656289
Background: A bridge-enhanced anterior cruciate ligament (ACL) repair (BEAR) procedure places an extracellular matrix implant, combined with autologous whole blood, in the gap between the torn ends of the ligament...
17.
Ayturk U, Sieker J, Haslauer C, Proffen B, Weissenberger M, Warman M, et al.
PLoS One
. 2020 Feb;
15(2):e0229449.
PMID: 32107493
Anterior cruciate ligament (ACL) transection surgery in the minipig induces post-traumatic osteoarthritis (PTOA) in a pattern similar to that seen in human patients after ACL injury. Prior studies have reported...
18.
OKeefe R, Tuan R, Lane N, Awad H, Barry F, Bunnell B, et al.
J Orthop Res
. 2020 Jan;
38(3):485-502.
PMID: 31994782
Cell-based therapies, defined here as the delivery of cells in vivo to treat disease, have recently gained increasing public attention as a potentially promising approach to restore structure and function...
19.
OKeefe R, Tuan R, Lane N, Awad H, Barry F, Bunnell B, et al.
J Bone Miner Res
. 2019 Sep;
35(1):3-17.
PMID: 31545883
Cell-based therapies, defined here as the delivery of cells in vivo to treat disease, have recently gained increasing public attention as a potentially promising approach to restore structure and function...
20.
Beveridge J, Proffen B, Karamchedu N, Chin K, Sieker J, Badger G, et al.
J Orthop Res
. 2019 May;
37(10):2249-2257.
PMID: 31125133
Inferior anterior cruciate ligament (ACL) structural properties may inadequately restrain tibiofemoral joint motion following surgery, contributing to the increased risk of post-traumatic osteoarthritis. Using both a direct measure of ACL...