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Bela Anand-Apte

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Articles 64
Citations 1712
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Recent Articles
1.
Jang G, Crabb J, Grenell A, Wolk A, Campla C, Luo S, et al.
Biol Sex Differ . 2024 Oct; 15(1):87. PMID: 39478535
Background: Sex as a biological variable is not a common consideration in molecular mechanistic or preclinical studies of retinal diseases. Understanding the sexual dimorphism of adult RPE and retina under...
2.
Dalvi S, Roll M, Chatterjee A, Kumar L, Bhogavalli A, Foley N, et al.
Dev Cell . 2024 Oct; 59(24):3290-3305.e9. PMID: 39362220
Age-related macular degeneration (AMD) and related macular dystrophies (MDs) primarily affect the retinal pigment epithelium (RPE) in the eye. A hallmark of AMD/MDs that drives later-stage pathologies is drusen. Drusen...
3.
Song P, Parsana D, Singh R, Pollock L, Anand-Apte B, Perkins B
Sci Rep . 2024 Aug; 14(1):20146. PMID: 39209978
Microglia are resident immune cells in the central nervous system, including the retina that surveil the environment for damage and infection. Following retinal damage, microglia undergo morphological changes, migrate to...
4.
Grenell A, Singh C, Raju M, Wolk A, Dalvi S, Jang G, et al.
Mol Metab . 2024 Jul; 88():101995. PMID: 39047907
Objectives: Mutations in Tissue Inhibitor of Metalloproteinases 3 (TIMP3) cause Sorsby's Fundus Dystrophy (SFD), a dominantly inherited, rare form of macular degeneration that results in vision loss. TIMP3 is synthesized...
5.
Singuri S, Luo S, Hatipoglu D, Nowacki A, Patel R, Schachat A, et al.
Ophthalmic Surg Lasers Imaging Retina . 2023 Dec; 54(12):692-700. PMID: 38113360
Background And Objective: Disorganization of retinal inner layers (DRIL) is a potential spectral-domain optical coherence tomography (SD-OCT) imaging biomarker with clinical utility in diabetic retinopathy (DR). Patients And Methods: A...
6.
Singh R, Singuri S, Batoki J, Lin K, Luo S, Hatipoglu D, et al.
Transl Vis Sci Technol . 2023 Jul; 12(7):6. PMID: 37410472
Purpose: To develop and train a deep learning-based algorithm for detecting disorganization of retinal inner layers (DRIL) on optical coherence tomography (OCT) to screen a cohort of patients with diabetic...
7.
Qi J, Anand-Apte B
Int J Mol Sci . 2022 Nov; 23(22). PMID: 36430707
Sorsby fundus dystrophy (SFD) is an autosomal dominant macular disorder caused by mutations in tissue Inhibitor of the metalloproteinase-3 ( gene with the onset of symptoms including choroidal neovascularization as...
8.
Mey G, Evonuk K, Chappell M, Wolfe L, Singh R, Batoki J, et al.
Acta Neuropathol Commun . 2022 Jul; 10(1):104. PMID: 35841033
No abstract available.
9.
Mey G, Evonuk K, Chappell M, Wolfe L, Singh R, Batoki J, et al.
Acta Neuropathol Commun . 2022 Jun; 10(1):87. PMID: 35706005
Thalamic volume is associated with clinical disability in multiple sclerosis (MS) and is vulnerable to secondary neurodegeneration due to its extensive connectivity throughout the central nervous system (CNS). Using a...
10.
Engel A, Wang Y, Khuu T, Worrall E, Manson M, Lim R, et al.
Exp Eye Res . 2021 Dec; 215:108899. PMID: 34929159
Sorsby Fundus Dystrophy (SFD) is a rare form of macular degeneration that is clinically similar to age-related macular degeneration (AMD), and a histologic hallmark of SFD is a thick layer...