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Beatrice Babbs

Explore the profile of Beatrice Babbs including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 280
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Recent Articles
1.
Persenaire C, Babbs B, Yamamoto T, Nebbia M, Jordan K, Adams S, et al.
Mol Carcinog . 2024 Apr; 63(7):1248-1259. PMID: 38558423
Epithelial ovarian cancers that are nonhomologous recombination deficient, as well as those that are recurrent and in a platinum-resistant state, have limited therapeutic options. The objectives of this study were...
2.
Petrache I, Pujadas E, Ganju A, Serban K, Borowiec A, Babbs B, et al.
JCI Insight . 2023 May; 8(10). PMID: 37212278
The pathogenesis of the marked pulmonary microvasculature injury, a distinguishing feature of COVID-19 acute respiratory distress syndrome (COVID-ARDS), remains unclear. Implicated in the pathophysiology of diverse diseases characterized by endothelial...
3.
Gordon M, Babbs B, Cochrane D, Bitler B, Richer J
Mol Carcinog . 2018 Oct; 58(2):196-205. PMID: 30294913
Ovarian cancer metastasizes via direct seeding, whereby cancer cells shed from the primary site, resist cell death in the peritoneal cavity, then metastasize to peritoneal organs. We sought to identify...
4.
Barton V, Christenson J, Gordon M, Greene L, Rogers T, Butterfield K, et al.
Cancer Res . 2017 May; 77(13):3455-3466. PMID: 28512248
Preclinical and early clinical trials indicate that up to 50% of triple-negative breast cancers (TNBC) express androgen receptor (AR) and are potentially responsive to antiandrogens. However, the function of AR...
5.
Gordon M, DAmato N, Gu H, Babbs B, Wulfkuhle J, Petricoin E, et al.
Mol Cancer Ther . 2017 May; 16(7):1389-1400. PMID: 28468774
The androgen receptor (AR) is widely expressed in breast cancer, and evidence suggests dependence on AR signaling for growth and survival. AR antagonists such as enzalutamide and seviteronel have shown...
6.
DAmato N, Gordon M, Babbs B, Spoelstra N, Carson Butterfield K, Torkko K, et al.
Mol Cancer Res . 2016 Aug; 14(11):1054-1067. PMID: 27565181
Implications: This study suggests that AR plays a previously unrecognized role in supporting E2-mediated ER activity in ER/AR breast cancer cells, and that enzalutamide may be an effective therapeutic in...
7.
Kucherov A, Polotsky A, Menke M, Isaac B, McAvey B, Buyuk E, et al.
Fertil Steril . 2011 Mar; 95(6):2063-6. PMID: 21353673
Objective: To better understand the site and mode of action of aromatase inhibitors. Design: Prospective study. Setting: Academic research environment. Patient(s): Five eumenorrheic (without polycystic ovary syndrome), early follicular phase...
8.
Bascom-Slack C, Ma C, Moore E, Babbs B, Fenn K, Greene J, et al.
Microb Ecol . 2009 Mar; 58(2):374-83. PMID: 19252940
Microbial biodiversity provides an increasingly important source of medically and industrially useful compounds. We have isolated 14 actinomycete species from a collection of approximately 300 plant stem samples from the...
9.
Smith S, Tank D, Boulanger L, Bascom-Slack C, Eisenman K, Kingery D, et al.
PLoS One . 2008 Aug; 3(8):e3052. PMID: 18725962
Background: A key argument in favor of conserving biodiversity is that as yet undiscovered biodiversity will yield products of great use to humans. However, the link between undiscovered biodiversity and...