Beata U Gajewska
Overview
Explore the profile of Beata U Gajewska including associated specialties, affiliations and a list of published articles.
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12
Citations
657
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Recent Articles
1.
Johnson J, Swirski F, Gajewska B, Wiley R, Fattouh R, Pacitto S, et al.
Am J Physiol Lung Cell Mol Physiol
. 2007 Jun;
293(3):L730-9.
PMID: 17586699
Asthma is a chronic airway inflammatory disease that encompasses three cardinal processes: T helper (Th) cell type 2 (Th2)-polarized inflammation, bronchial hyperreactivity, and airway wall remodeling. However, the link between...
2.
Suh W, Wang S, Duncan G, Miyazaki Y, Cates E, Walker T, et al.
Mol Cell Biol
. 2006 Aug;
26(17):6403-11.
PMID: 16914726
Members of the B7 family of cosignaling molecules regulate T-cell proliferation and effector functions by engaging cognate receptors on T cells. In vitro and in vivo blockade experiments indicated that...
3.
Lyddane C, Gajewska B, Santos E, King P, Furtado G, Sadelain M
J Immunol
. 2006 Mar;
176(6):3306-10.
PMID: 16517696
Ligation of CD28 during Ag recognition plays an important role in the generation of effective T cell responses. However, its peripheral control of regulatory T cell function remains obscure. In...
4.
Gajewska B, Tafuri A, Swirski F, Walker T, Johnson J, Shea T, et al.
J Immunol
. 2005 Feb;
174(5):3000-5.
PMID: 15728513
The recently described ICOS-B7RP-1 costimulatory pathway has been implicated in the generation of effector Th2 responses and, hence, has become an attractive therapeutic target for allergic diseases. In the present...
5.
Swirski F, Gajewska B, Robbins C, DSa A, Johnson J, Pouladi M, et al.
Eur J Immunol
. 2004 Aug;
34(9):2375-86.
PMID: 15307170
We previously showed that granulocyte-macrophage colony-stimulating factor (GM-CSF) breaks tolerance induction. The objective of this study was to determine whether GM-CSF breaks established inhalation tolerance. To induce tolerance, BALB/c mice...
6.
Continuous exposure to house dust mite elicits chronic airway inflammation and structural remodeling
Johnson J, Wiley R, Fattouh R, Swirski F, Gajewska B, Coyle A, et al.
Am J Respir Crit Care Med
. 2003 Nov;
169(3):378-85.
PMID: 14597485
It is now fully appreciated that asthma is a disease of a chronic nature resulting from intermittent or continued aeroallergen exposure leading to airway inflammation. To investigate responses to continuous...
7.
Gajewska B, Wiley R, Jordana M
Curr Drug Targets Inflamm Allergy
. 2003 Oct;
2(4):279-92.
PMID: 14561147
The interaction between dendritic cells (DC) and naïve T cells is the first step in the evolution of an immune response, either tolerogenic or inflammatory. Therefore, the status of DC...
8.
Suh W, Gajewska B, Okada H, Gronski M, Bertram E, Dawicki W, et al.
Nat Immunol
. 2003 Aug;
4(9):899-906.
PMID: 12925852
We investigated the in vivo function of the B7 family member B7-H3 (also known as B7RP-2) by gene targeting. B7-H3 inhibited T cell proliferation mediated by antibody to T cell...
9.
Mak T, Shahinian A, Yoshinaga S, Wakeham A, Boucher L, Pintilie M, et al.
Nat Immunol
. 2003 Jul;
4(8):765-72.
PMID: 12833154
Costimulation through the inducible costimulator (ICOS) and its ligand (ICOSL) is essential for T cell-dependent B cell responses, but the cellular and temporal dynamics underlying its in vivo effects are...
10.
Cates E, Gajewska B, Goncharova S, Alvarez D, Fattouh R, Coyle A, et al.
J Allergy Clin Immunol
. 2003 May;
111(5):1076-86.
PMID: 12743573
Background: Conventional models of allergic airway inflammation involve intraperitoneal administration of ovalbumin in conjunction with a chemical adjuvant (generally aluminum hydroxide) to generate allergic airways inflammation. Here we have investigated...