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Beata Tryniszewska

Explore the profile of Beata Tryniszewska including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 187
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Recent Articles
1.
Yu H, Kistler A, Faridi M, Meyer J, Tryniszewska B, Mehta D, et al.
J Am Soc Nephrol . 2016 Mar; 27(11):3308-3319. PMID: 27020855
Gain-of-function mutations of classic transient receptor potential channel 6 (TRPC6) were identified in familial FSGS, and increased expression of wild-type TRPC6 in glomeruli is observed in several human acquired proteinuric...
2.
Kc R, Li X, Forsyth C, Voigt R, Summa K, Vitaterna M, et al.
Sci Rep . 2015 Nov; 5:16896. PMID: 26584570
A variety of environmental factors contribute to progressive development of osteoarthritis (OA). Environmental factors that upset circadian rhythms have been linked to various diseases. Our recent work establishes chronic environmental...
3.
Kurko J, Vida A, Ocsko T, Tryniszewska B, Rauch T, Glant T, et al.
PLoS One . 2014 Nov; 9(11):e111815. PMID: 25369029
Background: Myeloid-derived suppressor cells (MDSCs) are innate immune cells capable of suppressing T-cell responses. We previously reported the presence of MDSCs with a granulocytic phenotype in the synovial fluid (SF)...
4.
Glant T, Besenyei T, Kadar A, Kurko J, Tryniszewska B, Gal J, et al.
Arthritis Rheum . 2013 May; 65(7):1725-35. PMID: 23653330
Objective: To identify epigenetic factors that are implicated in the pathogenesis of rheumatoid arthritis (RA), and to explore the therapeutic potential of the targeted inhibition of these factors. Methods: Polymerase...
5.
Besenyei T, Kadar A, Tryniszewska B, Kurko J, Rauch T, Glant T, et al.
Clin Dev Immunol . 2012 Dec; 2012:284751. PMID: 23251214
Rheumatoid arthritis (RA) is a polygenic autoimmune disease primarily affecting the synovial joints. Numerous animal models show similarities to RA in humans; some of them not only mimic the clinical...
6.
Egelston C, Kurko J, Besenyei T, Tryniszewska B, Rauch T, Glant T, et al.
Arthritis Rheum . 2012 Apr; 64(10):3179-88. PMID: 22492217
Objective: To determine whether myeloid cells (such as granulocytes) present in the synovial fluid (SF) of arthritic joints have an impact on adaptive immunity. Specifically, we investigated the effects of...
7.
Nagyeri G, Radacs M, Ghassemi-Nejad S, Tryniszewska B, Olasz K, Hutas G, et al.
J Biol Chem . 2011 May; 286(26):23559-69. PMID: 21566135
TSG-6 (TNF-α-stimulated gene/protein 6), a hyaluronan (HA)-binding protein, has been implicated in the negative regulation of inflammatory tissue destruction. However, little is known about the tissue/cell-specific expression of TSG-6 in...
8.
Nesterovitch A, Gyorfy Z, Hoffman M, Moore E, Elbuluk N, Tryniszewska B, et al.
Am J Pathol . 2011 Mar; 178(4):1434-41. PMID: 21406173
We have found a B2 repeat insertion in the gene encoding protein tyrosine phosphatase nonreceptor type 6 (PTPN6) in a mouse that developed a skin disorder with clinical and histopathological...
9.
Farkas B, Boldizsar F, Tarjanyi O, Laszlo A, Lin S, Hutas G, et al.
Arthritis Res Ther . 2009 Feb; 11(1):R21. PMID: 19220900
Introduction: The major histocompatibility complex (H-2d) and non-major histocompatibility complex genetic backgrounds make the BALB/c strain highly susceptible to inflammatory arthritis and spondylitis. Although different BALB/c colonies develop proteoglycan-induced arthritis...