Bas van Gerwen
Overview
Explore the profile of Bas van Gerwen including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
3
Citations
154
Followers
0
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Related Specialties
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Top 10 Co-Authors
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Published In
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Recent Articles
1.
Annunziato S, Lutz C, Henneman L, Bhin J, Wong K, Siteur B, et al.
EMBO J
. 2020 Jan;
39(5):e102169.
PMID: 31930530
Genetically engineered mouse models (GEMMs) of cancer have proven to be of great value for basic and translational research. Although CRISPR-based gene disruption offers a fast-track approach for perturbing gene...
2.
Annunziato S, de Ruiter J, Henneman L, Brambillasca C, Lutz C, Vaillant F, et al.
Nat Commun
. 2019 Jan;
10(1):397.
PMID: 30674894
BRCA1-mutated breast cancer is primarily driven by DNA copy-number alterations (CNAs) containing large numbers of candidate driver genes. Validation of these candidates requires novel approaches for high-throughput in vivo perturbation...
3.
Annunziato S, Kas S, Nethe M, Yucel H, Del Bravo J, Pritchard C, et al.
Genes Dev
. 2016 Jun;
30(12):1470-80.
PMID: 27340177
Large-scale sequencing studies are rapidly identifying putative oncogenic mutations in human tumors. However, discrimination between passenger and driver events in tumorigenesis remains challenging and requires in vivo validation studies in...