Bart W Bardoel
Overview
Explore the profile of Bart W Bardoel including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
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Snapshot
Articles
33
Citations
794
Followers
0
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Recent Articles
11.
Doorduijn D, Heesterbeek D, Ruyken M, de Haas C, Stapels D, Aerts P, et al.
PLoS Pathog
. 2022 Aug;
18(8):e1010758.
PMID: 35939488
[This corrects the article DOI: 10.1371/journal.ppat.1010051.].
12.
de Jong H, Moure M, Hartman J, Bosman G, Ong J, Bardoel B, et al.
Chembiochem
. 2022 Jul;
23(19):e202200340.
PMID: 35877976
The interactions between bacteria and their host often rely on recognition processes that involve host or bacterial glycans. Glycoengineering techniques make it possible to modify and study the glycans on...
13.
van Os N, Javed A, Broere F, van Dijk A, Balhuizen M, van Eijk M, et al.
J Glob Antimicrob Resist
. 2022 Jul;
30:406-413.
PMID: 35840108
Objectives: Our group recently developed a new group of antimicrobial peptides termed PepBiotics, of which peptides CR-163 and CR-172 showed optimized antibacterial activity against Pseudomonas aeruginosa and Staphylococcus aureus without...
14.
Spaan A, Neehus A, Laplantine E, Staels F, Ogishi M, Seeleuthner Y, et al.
Science
. 2022 May;
376(6599):eabm6380.
PMID: 35587511
The molecular basis of interindividual clinical variability upon infection with is unclear. We describe patients with haploinsufficiency for the linear deubiquitinase OTULIN, encoded by a gene on chromosome 5p. Patients...
15.
Doorduijn D, Heesterbeek D, Ruyken M, de Haas C, Stapels D, Aerts P, et al.
PLoS Pathog
. 2021 Nov;
17(11):e1010051.
PMID: 34752492
Complement proteins can form membrane attack complex (MAC) pores that directly kill Gram-negative bacteria. MAC pores assemble by stepwise binding of C5b, C6, C7, C8 and finally C9, which can...
16.
Heesterbeek D, Muts R, van Hensbergen V, de Saint Aulaire P, Wennekes T, Bardoel B, et al.
PLoS Pathog
. 2021 Jan;
17(1):e1009227.
PMID: 33481964
Infections with Gram-negative bacteria form an increasing risk for human health due to antibiotic resistance. Our immune system contains various antimicrobial proteins that can degrade the bacterial cell envelope. However,...
17.
Bacterial killing by complement requires direct anchoring of membrane attack complex precursor C5b-7
Doorduijn D, Bardoel B, Heesterbeek D, Ruyken M, Benn G, Parsons E, et al.
PLoS Pathog
. 2020 Jun;
16(6):e1008606.
PMID: 32569291
An important effector function of the human complement system is to directly kill Gram-negative bacteria via Membrane Attack Complex (MAC) pores. MAC pores are assembled when surface-bound convertase enzymes convert...
18.
Tromp A, van Gent M, Jansen J, Scheepmaker L, Velthuizen A, de Haas C, et al.
Toxins (Basel)
. 2020 Feb;
12(2).
PMID: 32041354
Staphylococcal bi-component pore-forming toxins, also known as leukocidins, target and lyse human phagocytes in a receptor-dependent manner. S-components of the leukocidins Panton-Valentine leukocidin (PVL), γ-haemolysin AB (HlgAB) and CB (HlgCB),...
19.
Heesterbeek D, Bardoel B, Parsons E, Bennett I, Ruyken M, Doorduijn D, et al.
EMBO J
. 2019 Jan;
38(4).
PMID: 30643019
The immune system kills bacteria by the formation of lytic membrane attack complexes (MACs), triggered when complement enzymes cleave C5. At present, it is not understood how the MAC perturbs...
20.
Tromp A, van Gent M, Abrial P, Martin A, Jansen J, de Haas C, et al.
Nat Microbiol
. 2018 Sep;
3(10):1187.
PMID: 30177744
In the version of this Article originally published, the name of author Robert Jan Lebbink was coded wrongly, resulting in it being incorrect when exported to citation databases. This has...