Bart J Van der Auwera
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Explore the profile of Bart J Van der Auwera including associated specialties, affiliations and a list of published articles.
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10
Citations
173
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Recent Articles
1.
Vandewalle J, Desouter A, Van der Auwera B, Tenoutasse S, Gillard P, De Block C, et al.
Clin Exp Immunol
. 2023 Jan;
211(3):224-232.
PMID: 36622793
The HLA region is the major genetic risk determinant of Type 1 diabetes. How non-HLA loci contribute to the genetic risk is incompletely understood, but there are indications that at...
2.
de Filette J, Andre S, De Mey L, Aspeslagh S, Karmali R, Van der Auwera B, et al.
BMC Endocr Disord
. 2022 Nov;
22(1):291.
PMID: 36419114
Background: Immune checkpoint inhibitors (ICI) targeting cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), programmed cell death protein 1 and its ligand (PD-1/PD-L1) have become the current standard-of-care for advanced cancers. This novel...
3.
Vandewalle J, Van der Auwera B, Amin H, Quartier E, Desouter A, Tenoutasse S, et al.
Diabetologia
. 2021 Aug;
64(11):2511-2516.
PMID: 34448034
Aims/hypothesis: We examined whether the non-HLA susceptibility locus ERBB3/IKZF4 influences progression of type 1 diabetes stage specifically according to sex. Methods: SNPs of ERBB3 (rs2292239 T/G) and IKZF4 (rs1701704 G/T)...
4.
de Filette J, Pen J, Decoster L, Vissers T, Bravenboer B, Van der Auwera B, et al.
Eur J Endocrinol
. 2019 Jul;
181(3):363-374.
PMID: 31330498
Objective: To better define the rare adverse event (AE) of diabetes mellitus associated with immune checkpoint inhibitors (ICIs). Design And Methods: We report the case of a lung cancer patient...
5.
Balke E, Demeester S, Lee D, Gillard P, Hilbrands R, Van de Velde U, et al.
Diabetologia
. 2018 Apr;
61(7):1623-1632.
PMID: 29679103
Aims/hypothesis: HLA-A*24 carriership hampers achievement of insulin independence in islet allograft recipients. However, less than half of those who fail to achieve insulin independence carry the allele. We investigated whether...
6.
Demeester S, Balke E, Van der Auwera B, Gillard P, Hilbrands R, Lee D, et al.
Diabetes Care
. 2016 May;
39(6):1060-4.
PMID: 27208324
Objective: We investigated whether changes in islet autoantibody profile and presence of HLA risk markers, reported to predict rapid β-cell loss in pre-type 1 diabetes, associate with poor functional outcome...
7.
Mbunwe E, Van der Auwera B, Vermeulen I, Demeester S, Van Dalem A, Balti E, et al.
Diabetes
. 2012 Nov;
62(4):1345-50.
PMID: 23160529
We investigated whether HLA-A*24 typing complements screening for HLA-DQ and for antibodies (Abs) against insulin, GAD, IA-2 (IA-2A), and zinc transporter-8 (ZnT8A) for prediction of rapid progression to type 1...
8.
Aminkeng F, Van Autreve J, Weets I, Quartier E, van Schravendijk C, Gorus F, et al.
Hum Immunol
. 2009 Jun;
70(9):706-10.
PMID: 19539001
The evaluation of susceptibility loci in a registry-based setting could be an important addition to the current predictive and screening models in T1D. Therefore, the aim of this study was...
9.
Van Autreve J, Weets I, Gulbis B, Vertongen F, Gorus F, Van der Auwera B
Hum Immunol
. 2004 Aug;
65(7):729-36.
PMID: 15301863
The heterozygous combination of DQA1*03-DQB1*0302 (DQ8) and DQA1*05-DQB1*0201 (DQ2) confers the highest known HLA-DQ-linked risk for type 1 diabetes, suggesting a role for transcomplementation. The trans-heterodimer encoded by DQA1*03 and...
10.
Van der Auwera B, Schuit F, Weets I, Ivens A, Van Autreve J, Gorus F
Hum Immunol
. 2002 Mar;
63(1):40-50.
PMID: 11916169
HLA-DQ genotyping remains the cornerstone of genetic risk stratification in type I diabetes prediction and prevention studies. We developed a genetic screening strategy for predisposition to type I diabetes in...