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Barry Finzel

Explore the profile of Barry Finzel including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 67
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Recent Articles
1.
Shah R, Peterson C, Strom A, Dillenburg M, Finzel B, Kitto K, et al.
ACS Chem Neurosci . 2019 Sep; 10(10):4385-4393. PMID: 31503445
The interactions between the mu-opioid (MOR) and -methyl-d-aspartate receptor (NMDAR) constitute an area of intense investigation because of their contributions to maladaptive neuroplasticity. Recent evidence suggests that their association requires...
2.
Liu L, Finzel B
Acta Crystallogr F Struct Biol Commun . 2014 Sep; 70(Pt 9):1155-61. PMID: 25195884
Two new crystal structures of the extracellular hyaluronan-binding domain of human CD44 are described at high resolution. A hexagonal crystal form at 1.60 Å resolution and a monoclinic form at...
3.
Evdokimov A, Mekel M, Hutchings K, Narasimhan L, Holler T, McGrath T, et al.
J Struct Biol . 2007 Dec; 162(1):152-69. PMID: 18086534
In this article, we describe for the first time the high-resolution crystal structure of a phenylalanine tRNA synthetase from the pathogenic bacterium Staphylococcus haemolyticus. We demonstrate the subtle yet important...
4.
Deur C, Agrawal A, Baum H, Booth J, Bove S, Brieland J, et al.
Bioorg Med Chem Lett . 2007 Jun; 17(16):4599-603. PMID: 17562362
It has been hypothesized that peripherally restricted NMDA receptor antagonists may be effective analgesics for osteoarthritis pain. A class of novel quinoxalinedione atropisomers, first discovered for an NMDA receptor antagonist...
5.
Bilder P, Lightle S, Bainbridge G, Ohren J, Finzel B, Sun F, et al.
Biochemistry . 2006 Feb; 45(6):1712-22. PMID: 16460018
Acetyl-coA carboxylase (ACC) is a central metabolic enzyme that catalyzes the committed step in fatty acid biosynthesis: biotin-dependent conversion of acetyl-coA to malonyl-coA. The bacterial carboxyltransferase (CT) subunit of ACC...