Barbara Perkins
Overview
Explore the profile of Barbara Perkins including associated specialties, affiliations and a list of published articles.
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9
Citations
358
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Recent Articles
1.
Guo Y, Andersen S, Shu X, Michailidou K, Bolla M, Wang Q, et al.
PLoS Med
. 2016 Aug;
13(8):e1002105.
PMID: 27551723
Background: Observational epidemiological studies have shown that high body mass index (BMI) is associated with a reduced risk of breast cancer in premenopausal women but an increased risk in postmenopausal...
2.
Hampras S, Sucheston-Campbell L, Cannioto R, Chang-Claude J, Modugno F, Dork T, et al.
Oncotarget
. 2016 Aug;
7(43):69097-69110.
PMID: 27533245
Background: Regulatory T (Treg) cells, a subset of CD4+ T lymphocytes, are mediators of immunosuppression in cancer, and, thus, variants in genes encoding Treg cell immune molecules could be associated...
3.
Zhao Z, Wen W, Michailidou K, Bolla M, Wang Q, Zhang B, et al.
Cancer Causes Control
. 2016 Apr;
27(5):679-93.
PMID: 27053251
Purpose: Type 2 diabetes (T2D) has been reported to be associated with an elevated risk of breast cancer. It is unclear, however, whether this association is due to shared genetic...
4.
Lin W, Camp N, Ghoussaini M, Beesley J, Michailidou K, Hopper J, et al.
Hum Mol Genet
. 2014 Aug;
24(1):285-98.
PMID: 25168388
Previous studies have suggested that polymorphisms in CASP8 on chromosome 2 are associated with breast cancer risk. To clarify the role of CASP8 in breast cancer susceptibility, we carried out...
5.
Doherty J, Rossing M, Cushing-Haugen K, Chen C, Van Den Berg D, Wu A, et al.
Cancer Epidemiol Biomarkers Prev
. 2010 Jan;
19(1):245-50.
PMID: 20056644
We genotyped 13 single nucleotide polymorphisms (SNPs) in the estrogen receptor alpha gene (ESR1) region in three population-based case-control studies of epithelial ovarian cancer conducted in the United States, comprising...
6.
Koessler T, Azzato E, Perkins B, MacInnis R, Greenberg D, Easton D, et al.
Int J Cancer
. 2008 Dec;
124(8):1887-91.
PMID: 19115210
The mismatch repair (MMR) genes are involved in the maintenance of genomic integrity. Recently, we showed that common variants in these genes are unlikely to contribute significantly to colorectal cancer...
7.
Samuelson D, Hesselson S, Aperavich B, Zan Y, Haag J, Trentham-Dietz A, et al.
Proc Natl Acad Sci U S A
. 2007 Apr;
104(15):6299-304.
PMID: 17404222
Breast cancer risk is a polygenic trait. To identify breast cancer modifier alleles that have a high population frequency and low penetrance we used a comparative genomics approach. Quantitative trait...
8.
Cebrian A, Pharoah P, Ahmed S, Ropero S, Fraga M, Smith P, et al.
Carcinogenesis
. 2006 Feb;
27(8):1661-9.
PMID: 16501248
Epigenetic events, resulting changes in gene expression capacity, are important in tumour progression, and variation in genes involved in epigenetic mechanisms might therefore be important in cancer susceptibility. To evaluate...
9.
Al-Zahrani A, Sandhu M, Luben R, Thompson D, Baynes C, Pooley K, et al.
Hum Mol Genet
. 2005 Nov;
15(1):1-10.
PMID: 16306136
Experimental and observational studies in humans and animals suggest that insulin-like growth factor 1 (IGF1) and its principal binding protein, IGFBP3, may influence breast cancer susceptibility. We have examined the...