Barbara Malinowska
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Explore the profile of Barbara Malinowska including associated specialties, affiliations and a list of published articles.
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70
Citations
573
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Recent Articles
1.
Pedzinska-Betiuk A, Gergs U, Weresa J, Remiszewski P, Harasim-Symbor E, Malinowska B
Pharmaceuticals (Basel)
. 2024 Oct;
17(10).
PMID: 39459019
Background: Hypoxia is one of the most significant pathogenic factors in cardiovascular diseases. Preclinical studies suggest that nonpsychoactive cannabidiol (CBD) and β-adrenoceptor stimulation might possess cardioprotective potential against ischemia-reperfusion injury....
2.
Harasim-Symbor E, Bielawiec P, Pedzinska-Betiuk A, Weresa J, Malinowska B, Konstantynowicz-Nowicka K, et al.
Nutr Metab Cardiovasc Dis
. 2024 Oct;
34(12):2817-2833.
PMID: 39358107
Background And Aims: Hypertension is a potent risk factor for cardiovascular diseases, which are the leading worldwide cause of death. Within time increased blood pressure (BP) induces cardiac contractile dysfunction,...
3.
Pedzinska-Betiuk A, Schlicker E, Weresa J, Malinowska B
Front Pharmacol
. 2024 Jun;
15:1382995.
PMID: 38873412
Ischemic heart disease, associated with high morbidity and mortality, represents a major challenge for the development of drug-based strategies to improve its prognosis. Results of pre-clinical studies suggest that agonists...
4.
Toczek M, Schlicker E, Remiszewski P, Malinowska B
Int J Mol Sci
. 2024 Jan;
25(2).
PMID: 38255931
We studied whether the function of presynaptic inhibitory cannabinoid CB receptors on the sympathetic nerve fibres innervating resistance vessels is increased in spontaneously hypertensive rats (SHR) like in deoxycorticosterone (DOCA)-salt...
5.
Toczek M, Ryszkiewicz P, Remiszewski P, Schlicker E, Krzyzewska A, Kozlowska H, et al.
Int J Mol Sci
. 2023 Jul;
24(13).
PMID: 37446125
The enhancement of the endocannabinoid tone might have a beneficial influence on hypertension. Polypharmacology proposes multi-target-directed ligands (MTDLs) as potential therapeutic agents for the treatment of complex diseases. In the...
6.
Ryszkiewicz P, Malinowska B, Schlicker E
Pharmacol Rep
. 2023 Jun;
75(4):755-770.
PMID: 37278927
Polypharmacology is an emerging strategy of design, synthesis, and clinical implementation of pharmaceutical agents that act on multiple targets simultaneously. It should not be mixed up with polytherapy, which is...
7.
Remiszewski P, Malinowska B
Pharmaceuticals (Basel)
. 2022 Sep;
15(9).
PMID: 36145339
Systemic and pulmonary hypertension are multifactorial, high-pressure diseases. The first one is a civilizational condition, and the second one is characterized by a very high mortality rate. Searching for new...
8.
Remiszewski P, Pedzinska-Betiuk A, Minczuk K, Schlicker E, Klimek J, Dzieciol J, et al.
Front Pharmacol
. 2022 Sep;
13:965613.
PMID: 36120288
Pulmonary hypertension (PH) is a disease leading to increased pressure in the pulmonary artery and right heart failure. The adenosine monophosphate-activated protein kinase (AMPK) activator, metformin, has a protective effect...
9.
Minczuk K, Baranowska-Kuczko M, Krzyzewska A, Schlicker E, Malinowska B
Int J Mol Sci
. 2022 Jun;
23(11).
PMID: 35683028
This review is dedicated to the cross-talk between the (endo)cannabinoid and renin angiotensin systems (RAS). Activation of AT receptors (ATRs) by angiotensin II (Ang II) can release endocannabinoids that, by...
10.
Minczuk K, Schlicker E, Malinowska B
Cells
. 2022 May;
11(9).
PMID: 35563848
We have previously shown that in urethane-anaesthetized rats, intravenous injection of the angiotensin II (Ang II) AT receptor antagonist losartan reversed the pressor effect of the cannabinoid CB receptor agonist...