Barbara K Kemp-Harper
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Explore the profile of Barbara K Kemp-Harper including associated specialties, affiliations and a list of published articles.
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1379
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Recent Articles
1.
Fu T, Mohan M, Bose M, Brennan E, Kiriazis H, Deo M, et al.
Cardiovasc Diabetol
. 2024 Nov;
23(1):413.
PMID: 39563316
Background: Diabetic heart disease may eventually lead to heart failure, a leading cause of mortality in diabetic individuals. The lack of effective treatments for diabetes-induced heart failure may result from...
2.
Hussain K, Lim H, Devkota S, Kemp-Harper B, Lane J, Canals M, et al.
PLoS One
. 2024 Sep;
19(9):e0305312.
PMID: 39259753
The primate-specific chemokine CCL18 is a potent chemoattractant for T cells and is expressed at elevated levels in several inflammatory diseases. However, the cognate receptor for CCL18 remains unconfirmed. Here,...
3.
Scott T, Lewis C, Zhu M, Wang C, Samuel C, Drummond G, et al.
Sci Rep
. 2023 Nov;
13(1):19589.
PMID: 37949903
In cardiovascular disease, pathological and protective roles are reported for the Th2 cytokines IL-4 and IL-13, respectively. We hypothesised that differential effects on macrophage function are responsible. Type I and...
4.
Liu Y, Croft K, Mori T, Gaspari T, Kemp-Harper B, Ward N
Eur J Nutr
. 2023 Feb;
62(4):1845-1857.
PMID: 36853380
Background And Aims: Atherosclerosis is associated with a reduction in the bioavailability and/or bioactivity of endogenous nitric oxide (NO). Dietary nitrate has been proposed as an alternate source when endogenous...
5.
Alam F, Gaspari T, Kemp-Harper B, Low E, Aw A, Ferens D, et al.
Biomed Pharmacother
. 2023 Feb;
160:114370.
PMID: 36753958
The hormone, relaxin (RLX), exerts various organ-protective effects independently of etiology. However, its complex two-chain and three disulphide bonded structure is a limitation to its preparation and affordability. Hence, a...
6.
Velagic A, Li M, Deo M, Li J, Kiriazis H, Donner D, et al.
Am J Physiol Heart Circ Physiol
. 2023 Jan;
324(2):H241-H257.
PMID: 36607798
Left ventricular (LV) dysfunction is an early, clinically detectable sign of cardiomyopathy in type 2 diabetes mellitus (T2DM) that precedes the development of symptomatic heart failure. Preclinical models of diabetic...
7.
Truong S, Bonnici B, Rupasinghe S, Kemp-Harper B, Samuel C, Broughton B
Pharmacol Res
. 2022 Dec;
187:106611.
PMID: 36526079
Brain inflammation and apoptosis contribute to neuronal damage and loss following ischaemic stroke, leading to cognitive and functional disability. It is well-documented that the human gene-2 (H2)-relaxin hormone exhibits pleiotropic...
8.
Velagic A, Li J, Qin C, Li M, Deo M, Marshall S, et al.
Br J Pharmacol
. 2022 Apr;
179(16):4117-4135.
PMID: 35365882
Background And Purpose: The risk of fatal cardiovascular events is increased in patients with type 2 diabetes mellitus (T2DM). A major contributor to poor prognosis is impaired nitric oxide (NO•)...
9.
Scott T, Qin C, Drummond G, Hobbs A, Kemp-Harper B
Hypertension
. 2021 Sep;
78(5):1168-1184.
PMID: 34565184
Pulmonary hypertension is a rare, ostensibly incurable, and etiologically diverse disease with an unacceptably high 5-year mortality rate (≈50%), worse than many cancers. Irrespective of pathogenic origin, dysregulated immune processes...
10.
Thomas J, Ling Y, Huuskes B, Jelinic M, Sharma P, Saini N, et al.
Hypertension
. 2021 Sep;
78(5):1296-1309.
PMID: 34488433
IL-18 (interleukin-18) is elevated in hypertensive patients, but its contribution to high blood pressure and end-organ damage is unknown. We examined the role of IL-18 in the development of renal...