Barbara Brauner
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Explore the profile of Barbara Brauner including associated specialties, affiliations and a list of published articles.
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17
Citations
1553
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Recent Articles
1.
Steinkamp R, Tsitsiridis G, Brauner B, Montrone C, Fobo G, Frishman G, et al.
Nucleic Acids Res
. 2024 Nov;
53(D1):D651-D657.
PMID: 39526397
CORUM (https://mips.helmholtz-muenchen.de/corum/) is a public database that offers comprehensive information about mammalian protein complexes, including their subunits, functions and associations with human diseases. The newly released CORUM 5.0, encompassing 7193...
2.
Tsitsiridis G, Steinkamp R, Giurgiu M, Brauner B, Fobo G, Frishman G, et al.
Nucleic Acids Res
. 2022 Nov;
51(D1):D539-D545.
PMID: 36382402
The CORUM database has been providing comprehensive reference information about experimentally characterized, mammalian protein complexes and their associated biological and biomedical properties since 2007. Given that most catalytic and regulatory...
3.
Baloni P, Arnold M, Buitrago L, Nho K, Moreno H, Huynh K, et al.
Commun Biol
. 2022 Oct;
5(1):1074.
PMID: 36209301
Dysregulation of sphingomyelin and ceramide metabolism have been implicated in Alzheimer's disease. Genome-wide and transcriptome-wide association studies have identified various genes and genetic variants in lipid metabolism that are associated...
4.
Ostaszewski M, Niarakis A, Mazein A, Kuperstein I, Phair R, Orta-Resendiz A, et al.
Mol Syst Biol
. 2021 Dec;
17(12):e10851.
PMID: 34939300
No abstract available.
5.
Ostaszewski M, Niarakis A, Mazein A, Kuperstein I, Phair R, Orta-Resendiz A, et al.
Mol Syst Biol
. 2021 Oct;
17(10):e10387.
PMID: 34664389
We need to effectively combine the knowledge from surging literature with complex datasets to propose mechanistic models of SARS-CoV-2 infection, improving data interpretation and predicting key targets of intervention. Here,...
6.
Arnold M, Nho K, Kueider-Paisley A, Massaro T, Huynh K, Brauner B, et al.
Nat Commun
. 2020 Mar;
11(1):1148.
PMID: 32123170
Late-onset Alzheimer's disease (AD) can, in part, be considered a metabolic disease. Besides age, female sex and APOE ε4 genotype represent strong risk factors for AD that also give rise...
7.
Giurgiu M, Reinhard J, Brauner B, Dunger-Kaltenbach I, Fobo G, Frishman G, et al.
Nucleic Acids Res
. 2018 Oct;
47(D1):D559-D563.
PMID: 30357367
CORUM is a database that provides a manually curated repository of experimentally characterized protein complexes from mammalian organisms, mainly human (67%), mouse (15%) and rat (10%). Given the vital functions...
8.
Adler A, Kirchmeier P, Reinhard J, Brauner B, Dunger I, Fobo G, et al.
Orphanet J Rare Dis
. 2018 Jan;
13(1):22.
PMID: 29370821
Background: Thoroughly annotated data resources are a key requirement in phenotype dependent analysis and diagnosis of diseases in the area of precision medicine. Recent work has shown that curation and...
9.
Liu X, Baarsma H, Thiam C, Montrone C, Brauner B, Fobo G, et al.
Cell Chem Biol
. 2016 Sep;
23(10):1302-1313.
PMID: 27667560
Phenotypic drug discovery offers some advantages over target-based methods, mainly because it allows drug leads to be tested in systems that more closely model distinct disease states. However, a potential...
10.
Lechner M, Hohn V, Brauner B, Dunger I, Fobo G, Frishman G, et al.
Genome Biol
. 2012 Jul;
13(7):R62.
PMID: 22809392
The pathobiology of common diseases is influenced by heterogeneous factors interacting in complex networks. CIDeR http://mips.helmholtz-muenchen.de/cider/ is a publicly available, manually curated, integrative database of metabolic and neurological disorders. The...