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Balbino Lino Dos Santos

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Citations 67
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Recent Articles
1.
Almeida A, Dos Santos C, Takahashi D, da Silva L, de Sousa V, de Santana M, et al.
Molecules . 2025 Mar; 30(5). PMID: 40076239
Nuclear receptors such as glucocorticoid receptors (GRs) are transcription factors with prominent regulatory effects on neuroinflammation. Agathisflavone is a biflavonoid that demonstrates neurogenic, neuroprotective, anti-inflammatory, antioxidant, and pro-myelinogenic effects in...
2.
de Sousa V, Almeida A, Ferreira R, Dos Santos B, da Silva V, David J, et al.
Int J Mol Sci . 2025 Feb; 26(3). PMID: 39941042
Traumatic brain injury (TBI) has a complex and multifactorial pathology and is a major cause of death and disability for humans. Immediately after TBI, astrocytes and microglia react with complex...
3.
da Silva K, Lima I, Dos Santos C, Nonaka C, Souza B, David J, et al.
Molecules . 2025 Jan; 30(1. PMID: 39795214
Glioblastomas (GBM) are malignant tumours with poor prognosis. Treatment involves chemotherapy and/or radiotherapy; however, there is currently no standard treatment for recurrence, and prognosis remains unfavourable. Inflammatory mediators and microRNAs...
4.
Dos Santos B, Dos Santos C, da Silva K, Nonaka C, Souza B, David J, et al.
Int J Mol Sci . 2024 Mar; 25(5). PMID: 38473794
MicroRNAs (miRs) act as important post-transcriptional regulators of gene expression in glial cells and have been shown to be involved in the pathogenesis of neurodegenerative diseases, including Alzheimer's disease (AD)....
5.
Lima I, Soares E, Nonaka C, Souza B, Dos Santos B, Costa S
Brain Sci . 2024 Jan; 14(1). PMID: 38248305
Glioblastoma (GBM) is the most aggressive and treatment-resistant brain tumor. In the GBM microenvironment, interaction with microglia is associated with the dysregulation of cytokines, chemokines, and miRNAs, contributing to angiogenesis,...
6.
Dos Santos B, Dos Santos C, Soares J, da Silva K, de Oliveira J, Pereira G, et al.
Pharmaceutics . 2023 May; 15(5). PMID: 37242652
Agathisflavone, purified from (Tul.) has been shown to be neuroprotective in in vitro models of glutamate-induced excitotoxicity and inflammatory damage. However, the potential role of microglial regulation by agathisflavone in...
7.
Nascimento R, Dos Santos B, Amparo J, Soares J, da Silva K, Santana M, et al.
Pharmaceutics . 2022 Jan; 14(1). PMID: 35057010
Glioblastomas (GBMs) are tumors that have a high ability to migrate, invade and proliferate in the healthy tissue, what greatly impairs their treatment. These characteristics are associated with the complex...
8.
Dourado N, Souza C, de Almeida M, da Silva A, Dos Santos B, Silva V, et al.
Front Aging Neurosci . 2020 Jun; 12:119. PMID: 32499693
Neurodegenerative disorders (ND) are characterized by the progressive and irreversible loss of neurons. Alzheimer's Disease (AD) is the most incident age-related ND, in which the presence of a chronic inflammatory...