Balbina J Plotkin
Overview
Explore the profile of Balbina J Plotkin including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
111
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Recent Articles
1.
Konaklieva M, Plotkin B
Antibiotics (Basel)
. 2024 Oct;
13(10).
PMID: 39452196
Bacteria have evolved and continue to change in response to environmental stressors including antibiotics. Antibiotic resistance and the ability to form biofilms are inextricably linked, requiring the continuous search for...
2.
Konaklieva M, Plotkin B
Front Mol Biosci
. 2024 Mar;
11:1338567.
PMID: 38455763
Microorganisms can takeover critical metabolic pathways in host cells to fuel their replication. This interaction provides an opportunity to target host metabolic pathways, in addition to the pathogen-specific ones, in...
3.
Plotkin B, Halkyard S, Spoolstra E, Micklo A, Kaminski A, Sigar I, et al.
Biology (Basel)
. 2023 Nov;
12(11).
PMID: 37998031
Methods: A variety of Gram-positive and Gram-negative bacteria were grown in peptone (1%) yeast nitrogen base broth overnight in 96-well plates with various concentrations of glucose and insulin. Biofilm formation...
4.
Konaklieva M, Plotkin B
Antibiotics (Basel)
. 2023 Sep;
12(9).
PMID: 37760715
The prevalence and continuing expansion of drug resistance, both in clinical and community settings represents a major challenge for current antimicrobial therapy. The different approaches for addressing this challenge include...
5.
Konaklieva M, Plotkin B
Antibiotics (Basel)
. 2023 Feb;
12(2).
PMID: 36830226
Fragment-based lead discovery (FBLD) is a powerful application for developing ligands as modulators of disease targets. This approach strategy involves identification of interactions between low-molecular weight compounds (100-300 Da) and...
6.
Patel N, Curtis J, Plotkin B
Antibiotics (Basel)
. 2021 Nov;
10(11).
PMID: 34827287
plays an important role in biofilm formation across a wide array of disease and ecological settings. Insulin can function as an adjuvant in the regulation of biofilm levels. The modulation...
7.
Prozialeck W, Edwards J, Lamar P, Plotkin B, Sigar I, Grundmann O, et al.
Int J Environ Res Public Health
. 2020 Aug;
17(15).
PMID: 32751712
Kratom (, Korth) is a tree-like plant that is indigenous to Southeast Asia. Kratom leaf products have been used in traditional folk medicine for their unique combination of stimulant and...
8.
Sigar I, Kaminski A, Ito B, Christoffersen-Cebi J, Vidovich A, Macarulay C, et al.
Curr Microbiol
. 2020 Apr;
77(8):1580-1589.
PMID: 32253468
Although Chlamydia infects host body regions that are hypoxic to anoxic, standard Chlamydiae culture conditions are in CO enriched (5%) atmospheric oxygen (21%). Because of its success in causing disease...
9.
Kuskovsky R, Lloyd D, Arora K, Plotkin B, Green J, Boshoff H, et al.
Bioorg Med Chem
. 2019 Sep;
27(20):115050.
PMID: 31474471
C4-phenylthio β-lactams are a new family of antibacterial agents that have activity against two phylogenetically distant bacteria - Mycobacterium tuberculosis (Mtb) and Moraxella catarrhalis (M. cat). These compounds are effective...
10.
Plotkin B, Sigar I, Swartzendruber J, Kaminski A
J Vis Exp
. 2018 Aug;
(137).
PMID: 30080196
Most mucosal surfaces along with the midpoints in tumors and stem cell niches are geographic areas of the body that are anoxic. Previous studies show that the incubation in normoxic...