Balasubramanian Krishnamurthy
Overview
Explore the profile of Balasubramanian Krishnamurthy including associated specialties, affiliations and a list of published articles.
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57
Citations
1110
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Recent Articles
1.
De George D, Jhala G, Selck C, Trivedi P, Brodnicki T, Mackin L, et al.
J Immunol
. 2024 Apr;
212(11):1658-1669.
PMID: 38587315
Chronic destruction of insulin-producing pancreatic β cells by T cells results in autoimmune diabetes. Similar to other chronic T cell-mediated pathologies, a role for T cell exhaustion has been identified...
2.
Trivedi P, Jhala G, De George D, Chiu C, Selck C, Ge T, et al.
Front Immunol
. 2024 Mar;
15:1370907.
PMID: 38533515
Introduction: Chronic activation of self-reactive T cells with beta cell antigens results in the upregulation of immune checkpoint molecules that keep self-reactive T cells under control and delay beta cell...
3.
Krishnamurthy B, Thomas H
Nat Cell Biol
. 2024 Feb;
26(3):321-322.
PMID: 38409326
No abstract available.
4.
Deitch J, Lee I, Yates C, Kathpal E, Lawton P, Shahid I, et al.
Diabetes Res Clin Pract
. 2024 Feb;
209:111120.
PMID: 38307138
Aims: The study aimed to evaluate the impact of a simplified screeningapproach for gestational diabetes (GDM) compared to conventional screening on OGTT rates, GDM prevalence, and perinatal outcomes. Method: A...
5.
Selck C, Jhala G, De George D, Kwong C, Christensen M, Pappas E, et al.
Proc Natl Acad Sci U S A
. 2024 Jan;
121(6):e2315419121.
PMID: 38285952
Persistent antigen exposure results in the differentiation of functionally impaired, also termed exhausted, T cells which are maintained by a distinct population of precursors of exhausted T (T) cells. T...
6.
Galligan A, Wallace R, Krishnamurthy B, Kay T, Sachithanandan N, Chiang C, et al.
Cancers (Basel)
. 2023 Dec;
15(24).
PMID: 38136348
Background: FDG-PET/CT used for immune checkpoint inhibitor (ICI) response assessment can incidentally identify immune-related adverse events (irAEs), including thyroiditis. This study aimed to correlate the time course of FDG-PET/CT evidence...
7.
Galligan A, Iravani A, Lasocki A, Wallace R, Weppler A, Sachithanandan N, et al.
Front Endocrinol (Lausanne)
. 2023 Dec;
14:1295865.
PMID: 38093958
Introduction: Hypophysitis is reported in 8.5%-14% of patients receiving combination immune checkpoint inhibition (cICI) but can be a diagnostic challenge. This study aimed to assess the role of routine diagnostic...
8.
Waibel M, Wentworth J, So M, Couper J, Cameron F, MacIsaac R, et al.
N Engl J Med
. 2023 Dec;
389(23):2140-2150.
PMID: 38055252
Background: Janus kinase (JAK) inhibitors, including baricitinib, block cytokine signaling and are effective disease-modifying treatments for several autoimmune diseases. Whether baricitinib preserves β-cell function in type 1 diabetes is unclear....
9.
Krishnamurthy B, Lacorcia M, Kay T, Thomas H, Mannering S
Front Immunol
. 2023 Jun;
14:1206874.
PMID: 37346035
Type 1 diabetes (T1D) is a T-cell mediated autoimmune disease. Short-term treatment with agents targeting T cells, B cells and inflammatory cytokines to modify the disease course resulted in a...
10.
Donaldson L, Vogrin S, So M, Ward G, Krishnamurthy B, Sundararajan V, et al.
Diabetes Technol Ther
. 2023 Apr;
25(7):497-506.
PMID: 37010375
This study examined correlations between continuous glucose monitoring (CGM)-based composite metrics and standard glucose metrics within CGM data sets from individuals with recent-onset and long-duration type 1 diabetes. First, a...