Bagna Bao
Overview
Explore the profile of Bagna Bao including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
111
Followers
0
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Recent Articles
1.
Bao B, Vasquez K, Ho G, Zhang J, Delaney J, Rajopadhye M, et al.
J Pharmacol Exp Ther
. 2019 Jun;
370(2):288-298.
PMID: 31152006
In mouse pharmacokinetic (PK) studies, current standard methods often require large numbers of animals to support collection of blood samples serially over a defined time range. We have developed and...
2.
Tseng J, Narayanan N, Ho G, Groves K, Delaney J, Bao B, et al.
PLoS One
. 2017 Aug;
12(8):e0182689.
PMID: 28792505
Physical measurement of tumor volume reduction is the most commonly used approach to assess tumor progression and treatment efficacy in mouse tumor models. However, it is relatively insensitive, and often...
3.
Bao B, Groves K, Zhang J, Handy E, Kennedy P, Cuneo G, et al.
PLoS One
. 2012 Dec;
7(11):e50860.
PMID: 23226406
Carbonic anhydrase IX (CA IX) is a transmembrane protein that has been shown to be greatly upregulated under conditions of hypoxia in many tumor cell lines. Tumor hypoxia is associated...
4.
Lin S, Patel M, Suresch D, Connolly B, Bao B, Groves K, et al.
Int J Mol Imaging
. 2012 Nov;
2012:189254.
PMID: 23119157
Inflammation as a core pathological event of atherosclerotic lesions is associated with the secretion of cathepsin proteases and the expression of α(v)β(3) integrin. We employed fluorescence molecular tomographic (FMT) noninvasive...
5.
Zhang J, Preda D, Vasquez K, Morin J, Delaney J, Bao B, et al.
Am J Physiol Renal Physiol
. 2012 Jun;
303(4):F593-603.
PMID: 22674025
The renin-angiotensin system (RAS) is well studied for its regulation of blood pressure and fluid homeostasis, as well as for increased activity associated with a variety of diseases and conditions,...
6.
Gege C, Bao B, Bluhm H, Boer J, Gallagher B, Korniski B, et al.
J Med Chem
. 2011 Dec;
55(2):709-16.
PMID: 22175799
Osteoarthritis (OA) is a nonsystemic disease for which no oral or parenteral disease-modifying osteoarthritic drug (DMOAD) is currently available. Matrix metalloproteinase 13 (MMP-13) has attracted attention as a target with...
7.
Groves K, Bao B, Zhang J, Handy E, Kennedy P, Cuneo G, et al.
Bioorg Med Chem Lett
. 2011 Nov;
22(1):653-7.
PMID: 22079760
A series of human carbonic anhydrase (hCA) IX inhibitors conjugated to various near-infrared fluorescent dyes was synthesized with the aim of imaging hypoxia-induced hCA IX expression in tumor cells in...
8.
Xiao Y, Araldi G, Zhao Z, Reddy A, Karra S, Brugger N, et al.
Bioorg Med Chem Lett
. 2007 Nov;
18(2):821-4.
PMID: 18039575
Gamma-lactam analogs (2) of EP(4) receptor agonists were identified by substitution of the pyrazolidinone ring (1) with a pyrrolidinone ring. Several compounds (such as 2a, 2h) with high potency, selectivity...
9.
McKenna S, Pietropaolo M, Gillio Tos E, Clark A, Fischer D, Kagan D, et al.
Endocrinology
. 2004 Sep;
146(1):208-14.
PMID: 15448112
Phosphodiesterases (PDEs) are a family of enzymes that hydrolyze cyclic nucleotides to render them biologically inactive. As such, these enzymes are critical regulators of signal transduction pathways that use cyclic...