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Baerbel Lange-Sperandio

Explore the profile of Baerbel Lange-Sperandio including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 245
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Recent Articles
1.
Boeckhaus J, Tonshoff B, Weber L, Pape L, Latta K, Fehrenbach H, et al.
Pediatr Nephrol . 2025 Feb; PMID: 39904897
Background: Chronic kidney disease (CKD) seriously affects the well-being and shortens the life expectancy of children and adolescents, but its progression is challenging to predict. Therefore, there is an urgent...
2.
Immler R, Nussbaumer K, Doerner A, El Bounkari O, Huber S, Abisch J, et al.
Proc Natl Acad Sci U S A . 2024 Apr; 121(19):e2319057121. PMID: 38687790
Eosinophil recruitment is a pathological hallmark of many allergic and helminthic diseases. Here, we investigated chemokine receptor CCR3-induced eosinophil recruitment in sialyltransferase mice. We found a marked decrease in eosinophil...
3.
Boeckhaus J, Mohr L, Dihazi H, Tonshoff B, Weber L, Pape L, et al.
Cells . 2023 May; 12(9). PMID: 37174733
The urinary albumin- and protein-to-creatinine ratios (UACR and UPCR, respectively) are key endpoints in most clinical trials assessing risk of progression of chronic kidney disease (CKD). For the first time,...
4.
Wychera C, Imlay H, Duke E, Faino A, Li-Huang M, Stevens-Ayers T, et al.
Transplant Cell Ther . 2022 Dec; 29(3):187.e1-187.e8. PMID: 36494016
Kidney disease in allogeneic hematopoietic cell transplantation (HCT) recipients is associated with increased mortality rates. BK virus (BKV) viremia has been associated with kidney dysfunction in pediatric HCT recipients; however,...
5.
Boeckhaus J, Hoefele J, Riedhammer K, Tonshoff B, Ehren R, Pape L, et al.
Clin Genet . 2020 Oct; 99(1):143-156. PMID: 33040356
Early initiation of therapy in patients with Alport syndrome (AS) slows down renal failure by many years. Genotype-phenotype correlations propose that the location and character of the individual's variant correlate...
6.
Riedhammer K, Braunisch M, Gunthner R, Wagner M, Hemmer C, Strom T, et al.
Am J Kidney Dis . 2020 May; 76(4):460-470. PMID: 32359821
Rationale & Objective: Hereditary nephropathies are clinically and genetically heterogeneous disorders. For some patients, the clinical phenotype corresponds to a specific hereditary disease but genetic testing reveals that the expected...
7.
Gross O, Tonshoff B, Weber L, Pape L, Latta K, Fehrenbach H, et al.
Kidney Int . 2020 Apr; 97(6):1275-1286. PMID: 32299679
Children with Alport syndrome develop renal failure early in life. Since the safety and efficacy of preemptive nephroprotective therapy are uncertain we conducted a randomized, placebo-controlled, double-blind trial in 14...
8.
Nussbaum C, Bannenberg S, Keul P, Graler M, Goncalves-de-Albuquerque C, Korhonen H, et al.
Nat Commun . 2015 Apr; 6:6416. PMID: 25832730
Sphingosine-1-phosphate (S1P) participates in inflammation; however, its role in leukocyte rolling is still unclear. Here we use intravital microscopy in inflamed mouse cremaster muscle venules and human endothelial cells to...
9.
Frommhold D, Kamphues A, Dannenberg S, Buschmann K, Zablotskaya V, Tschada R, et al.
BMC Immunol . 2011 Oct; 12:56. PMID: 21970746
Background: The receptor for advanced glycation endproducts, RAGE, is involved in the pathogenesis of many inflammatory conditions, which is mostly related to its strong activation of NF-κB but also due...
10.
Frommhold D, Kamphues A, Hepper I, Pruenster M, Lukic I, Socher I, et al.
Blood . 2010 Apr; 116(5):841-9. PMID: 20407037
The receptor for advanced glycation end products (RAGE) contributes to the inflammatory response in many acute and chronic diseases. In this context, RAGE has been identified as a ligand for...