B Van Hoef
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Explore the profile of B Van Hoef including associated specialties, affiliations and a list of published articles.
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59
Citations
527
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Recent Articles
1.
Lijnen H, Van Hoef B, Rodriguez J, Paramo J
Biochem Biophys Res Commun
. 2009 Sep;
389(2):378-81.
PMID: 19732744
Adipose tissue development is associated with angiogenesis, adipogenesis and extracellular matrix degradation. The class of matrix metalloproteinases contributes to these processes, but little information is available on the role of...
2.
Deficiency of vascular endothelial growth factor-D does not affect murine adipose tissue development
Lijnen H, Frederix L, Van Hoef B, Dewerchin M
Biochem Biophys Res Commun
. 2008 Nov;
378(2):255-8.
PMID: 19022221
Vascular endothelial growth factor (VEGF)-D deficiency had no significant effect on total body weight or on subcutaneous (SC) or gonadal (GON) adipose tissue mass of mice kept on a standard...
3.
Lijnen H, Van Hoef B, Kemp D, Collen D
Biochim Biophys Acta
. 2007 Jul;
1770(9):1369-73.
PMID: 17616257
We have studied the effect of PTK787 (Vatalanib), an inhibitor of vascular endothelial growth factor receptor (VEGFR) tyrosine kinases, on adipose tissue development. Oral administration of PTK787 for 4 weeks...
4.
Nagai N, Van Hoef B, Lijnen H
J Thromb Haemost
. 2007 Jun;
5(8):1726-31.
PMID: 17596132
Background: It is widely accepted that obesity is a risk factor for ischemic heart disease, but the association with stroke is less clear. Adipose tissue is an important source of...
5.
Nagai N, Suzuki Y, Van Hoef B, Lijnen H, Collen D
J Thromb Haemost
. 2005 Jun;
3(7):1379-84.
PMID: 15978095
Background And Objectives: Tissue plasminogen activator (t-PA) improves the outcome of ischemic stroke by recanalization of occluded vessels, but has neurotoxic side effects in experimental stroke models. Here, the effect...
6.
Lijnen H, Alessi M, Van Hoef B, Collen D, Juhan-Vague I
J Thromb Haemost
. 2005 Jun;
3(6):1174-9.
PMID: 15946208
Objectives: To investigate the role of plasminogen activator inhibitor-1 (PAI-1) in adipose tissue development and insulin metabolism. Methods: Aged male wild-type (WT) or transgenic mice with adipose tissue overexpression of...
7.
Lijnen H, Van Hoef B, Umans K, Collen D
J Thromb Haemost
. 2004 Jan;
2(1):16-22.
PMID: 14717961
The controversial role of plasminogen activator inhibitor-1 (PAI-1) in neointima formation and restenosis was studied with the use of a vascular injury model in transgenic mice overexpressing murine PAI-1 (PAI-1...
8.
Nagai N, Demarsin E, Van Hoef B, Wouters S, Cingolani D, Laroche Y, et al.
J Thromb Haemost
. 2003 Jul;
1(2):307-13.
PMID: 12871505
The effect of recombinant human microplasmin was studied in ischemic stroke models in mice and in an extracorporeal loop thrombosis model in rabbits. Human microplasminogen ( micro Plg), which lacks...
9.
Lijnen H, Maquoi E, Hansen L, Van Hoef B, Frederix L, Collen D
Arterioscler Thromb Vasc Biol
. 2002 Mar;
22(3):374-9.
PMID: 11884277
The effect of galardin, a broad-spectrum matrix metalloproteinase (MMP) inhibitor, was studied in mice kept on a high fat diet (HFD). Five-week-old male wild-type mice were fed the HFD (42%...
10.
Morange P, Bastelica D, Bonzi M, Van Hoef B, Collen D, Juhan-Vague I, et al.
Thromb Haemost
. 2002 Feb;
87(2):306-10.
PMID: 11858492
To investigate the potential role of tissue-type plasminogen activator (t-PA) or urokinase-type plasminogen activator (u-PA) in development of adipose tissue, we have used a nutritionally induced obesity model in t-PA...