B Strulovici
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Explore the profile of B Strulovici including associated specialties, affiliations and a list of published articles.
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Articles
35
Citations
359
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Recent Articles
1.
Ross D, Lee S, Reiser V, Xue J, Alves K, Vaidya S, et al.
J Biomol Screen
. 2008 Jun;
13(6):449-55.
PMID: 18519922
G-protein-coupled receptors (GPCR) participate in many disease pathways and represent the largest family of therapeutic targets. Thus, great investments are made to discover drugs modulating GPCR-mediated events. Among functional assays...
2.
Zheng W, Carroll S, Inglese J, Graves R, Howells L, Strulovici B
Anal Biochem
. 2001 Mar;
290(2):214-20.
PMID: 11237322
Innovations in detection technologies have allowed us to develop a novel assay in 1536-well plate format and assess the advantages of screen miniaturization compared with conventional high-throughput compound screening in...
3.
Wu P, Daniel-Issakani S, LaMarco K, Strulovici B
Anal Biochem
. 1997 Feb;
245(2):226-30.
PMID: 9056217
A high throughput filtration assay was developed and automated for screening compounds and natural product extracts using 96-well filterplates. The selection of a hydrophobic membrane and appropriate capture conditions enabled...
4.
Lehel C, Daniel-Issakani S, Brasseur M, Strulovici B
Anal Biochem
. 1997 Jan;
244(2):340-6.
PMID: 9025951
A chemiluminescent protein kinase assay using biotinylated substrate peptides captured on a streptavidin-coated microtiter plate and monoclonal antibodies to detect their phosphorylation is described. Assay conditions were optimized and validated...
5.
Puceat M, Strulovici B, Brunton L, Brown J
J Biol Chem
. 1994 Jun;
269(24):16938-44.
PMID: 8207017
We have immunologically identified the isoforms of protein kinase C (PKC) present in neonatal and adult rat cardiomyocytes and examined their regulation by hormones and phorbol ester. Both cell types...
6.
Wang C, Constantinescu S, MacEwan D, Strulovici B, Dekker L, Parker P, et al.
Proc Natl Acad Sci U S A
. 1993 Aug;
90(15):6944-8.
PMID: 8346200
Protein kinases play key roles in the induction by human interferon alpha (IFN-alpha) of specific gene expression and biological activity in various human cell lines. We now report that IFN-alpha...
7.
Kim C, Giaccia A, Strulovici B, Brown J
Br J Cancer
. 1992 Nov;
66(5):844-9.
PMID: 1329908
The effect of ionising radiation on the regulation of gene and protein expression is complex. This study focuses on the translational regulational of the epsilon isoform of protein kinase C...
8.
Omary M, Baxter G, Chou C, Riopel C, Lin W, Strulovici B
J Cell Biol
. 1992 May;
117(3):583-93.
PMID: 1374067
A 40-kD protein kinase C (PKC)epsilon related activity was found to associate with human epithelial specific cytokeratin (CK) polypeptides 8 and 18. The kinase activity coimmunoprecipitated with CK8 and 18...
9.
Baxter G, Oto E, Daniel-Issakani S, Strulovici B
J Biol Chem
. 1992 Jan;
267(3):1910-7.
PMID: 1309802
Protein kinase C (PKC) has been implicated in a variety of cellular responses such as proliferation, differentiation, and secretion. We assessed the role of PKC in the mitogenic effects of...
10.
Pfeffer L, Eisenkraft B, Reich N, Improta T, Baxter G, Daniel-Issakani S, et al.
Proc Natl Acad Sci U S A
. 1991 Sep;
88(18):7988-92.
PMID: 1832772
The early events that occur after treatment of the highly interferon alpha (IFN-alpha)-sensitive human lymphoblastoid Daudi cell line with human leukocyte IFN-alpha have been examined. IFN-alpha treatment of Daudi cells...