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B N Pudota

Explore the profile of B N Pudota including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 4
Citations 58
Followers 0
Related Specialties
Biochemistry
Science
Top 10 Co-Authors
K L Berkner
E L Hommema
K W Hallgren
B A McNally
M Miyagi
O Stenina
K S Misono
J W Crabb
S Lee
K A West
Published In
Proc Natl Acad Sci U S A
Biochemistry
J Biol Chem
Affiliations
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Recent Articles
1.
Identification of sequences within the gamma-carboxylase that represent a novel contact site with vitamin K-dependent proteins and that are required for activity
Pudota B, Hommema E, Hallgren K, McNally B, Lee S, Berkner K
J Biol Chem . 2001 Oct; 276(50):46878-86. PMID: 11591726
The vitamin K-dependent (VKD) carboxylase converts clusters of Glu residues to gamma-carboxylated Glu residues (Glas) in VKD proteins, which is required for their activity. VKD precursors are targeted to the...
2.
Tethered processivity of the vitamin K-dependent carboxylase: factor IX is efficiently modified in a mechanism which distinguishes Gla's from Glu's and which accounts for comprehensive carboxylation in vivo
Stenina O, Pudota B, McNally B, Hommema E, Berkner K
Biochemistry . 2001 Aug; 40(34):10301-9. PMID: 11513608
The vitamin K-dependent (VKD) carboxylase binds VKD proteins via their propeptide and converts Glu's to gamma-carboxylated Glu's, or Gla's, in the Gla domain. Multiple carboxylation is required for activity, which...
3.
Identification of the vitamin K-dependent carboxylase active site: Cys-99 and Cys-450 are required for both epoxidation and carboxylation
Pudota B, Miyagi M, Hallgren K, West K, Crabb J, Misono K, et al.
Proc Natl Acad Sci U S A . 2000 Nov; 97(24):13033-8. PMID: 11087858
The vitamin K-dependent carboxylase modifies and renders active vitamin K-dependent proteins involved in hemostasis, cell growth control, and calcium homeostasis. Using a novel mechanism, the carboxylase transduces the free energy...
4.
Vitamin K-dependent carboxylation of the carboxylase
Berkner K, Pudota B
Proc Natl Acad Sci U S A . 1998 Jan; 95(2):466-71. PMID: 9435215
Vitamin K-dependent (VKD) proteins require modification by the VKD-gamma-glutamyl carboxylase, an enzyme that converts clusters of glus to glas in a reaction that requires vitamin K hydroquinone, for their activity....