B M Willardson
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Explore the profile of B M Willardson including associated specialties, affiliations and a list of published articles.
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18
Citations
340
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Recent Articles
1.
Thulin C, Savage J, McLaughlin J, Truscott S, Old W, Ahn N, et al.
J Biol Chem
. 2001 May;
276(26):23805-15.
PMID: 11331285
Phototransduction is a canonical G protein-mediated cascade of retinal photoreceptor cells that transforms photons into neural responses. Phosducin (Pd) is a Gbetagamma-binding protein that is highly expressed in photoreceptors. Pd...
2.
Martin M, Willardson B, Burton G, White C, McLaughlin J, Bray S, et al.
Mol Endocrinol
. 2001 Feb;
15(2):281-93.
PMID: 11158334
Human tissues that express the angiotensin II (Ang II) type 1 receptor (hAT(1)R) can synthesize four distinct alternatively spliced hAT(1)R mRNA transcripts. In this study, we show that the relative...
3.
Lazarov M, Martin M, Willardson B, Elton T
Biochim Biophys Acta
. 2000 Jul;
1492(2-3):460-4.
PMID: 10899582
Phosducin-like protein (PhLP) is an inducible Gbetagamma binding protein which is hypothesized to be a ubiquitous G protein regulator. To elucidate the mechanisms regulating the expression of the human PhLP...
4.
Savage J, McLaughlin J, Skiba N, Hamm H, Willardson B
J Biol Chem
. 2000 Jul;
275(39):30399-407.
PMID: 10896945
Phosducin and phosducin-like protein regulate G protein signaling pathways by binding the betagamma subunit complex (Gbetagamma) and blocking Gbetagamma association with Galpha subunits, effector enzymes, or membranes. Both proteins are...
5.
Thulin C, Howes K, Driscoll C, Savage J, Rand T, Baehr W, et al.
Mol Vis
. 2000 Jan;
5:40.
PMID: 10617777
Purpose: These investigations were undertaken to compare and contrast the roles of phosducin and phosducin-like protein in the retina. Methods: Phosducin and phosducin-like protein were compared in an in vitro...
6.
Lazarov M, Martin M, Willardson B, Elton T
Biochim Biophys Acta
. 1999 Oct;
1446(3):253-64.
PMID: 10524200
Phosducin (Pd) and phosducin-like protein (PhLP) have been shown to regulate G-protein signaling by binding G beta gamma subunits. To better define the function and regulation of PhLP, and to...
7.
Gaudet R, Savage J, McLaughlin J, Willardson B, SIGLER P
Mol Cell
. 1999 Jun;
3(5):649-60.
PMID: 10360181
Visual signal transduction is a nearly noise-free process that is exquisitely well regulated over a wide dynamic range of light intensity. A key component in dark/light adaptation is phosducin, a...
8.
Willardson B, Wilkins J, Rand T, Schupp J, Hill K, Keim P, et al.
Appl Environ Microbiol
. 1998 Mar;
64(3):1006-12.
PMID: 9501440
A bacterial biosensor for benzene, toluene, and similar compounds has been constructed, characterized, and field tested on contaminated water and soil. The biosensor is based on a plasmid incorporating the...
9.
Wilkins J, Bitensky M, Willardson B
J Biol Chem
. 1996 Aug;
271(32):19232-7.
PMID: 8702603
Phosducin (Pd) is a widely expressed phosphoprotein that regulates G-protein (G) signaling. Unphosphorylated Pd binds to Gbetagamma subunits and blocks their interaction with Galpha. This binding sequesters Gbetagamma and inhibits...
10.
Willardson B, Wilkins J, Yoshida T, Bitensky M
Proc Natl Acad Sci U S A
. 1996 Feb;
93(4):1475-9.
PMID: 8643657
The phosphoprotein phosducin (Pd) regulates many guanine nucleotide binding protein (G protein)-linked signaling pathways. In visual signal transduction, unphosphorylated Pd blocks the interaction of light-activated rhodopsin with its G protein...