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B I Kuslikis

Explore the profile of B I Kuslikis including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 86
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Recent Articles
1.
Vanden Heuvel J, Kuslikis B, Peterson R
Chem Biol Interact . 1992 May; 82(3):317-28. PMID: 1606626
Perfluorinated fatty acids alter hepatic lipid metabolism and are potent peroxisome proliferators in rodents. Two such perfluorinated acids, perfluorodecanoic acid (PFDA) and perfluorooctanoic acid (PFOA), were examined to determine if...
2.
Kuslikis B, Vanden Heuvel J, Peterson R
J Biochem Toxicol . 1992 Jan; 7(1):25-9. PMID: 1588571
Perfluorodecanoic (PFDA) and perfluorooctanoic (PFOA) acids belong to the structurally diverse group of compounds known to cause peroxisomal proliferation. It has been hypothesized that the common mode of action of...
3.
Vanden Heuvel J, Kuslikis B, Shrago E, Peterson R
Biochem Pharmacol . 1991 Jul; 42(2):295-302. PMID: 1859447
Perfluorodecanoic acid (PFDA) is a potent peroxisome proliferator and is known to affect hepatic lipid metabolism in rats. The effects of PFDA on fatty acid utilization were examined in isolated...
4.
Vanden Heuvel J, Kuslikis B, Van Rafelghem M, Peterson R
Toxicol Appl Pharmacol . 1991 Mar; 107(3):450-9. PMID: 2000633
The elimination, tissue distribution, and metabolism of [1-14C]PFDA were examined in male and female rats for 28 days after a single ip dose (9.4 mumol/kg, 5 mg/kg). A sex difference...
5.
Chen T, Kuslikis B, Braselton Jr W
Arch Toxicol . 1991 Jan; 65(3):177-85. PMID: 2053844
The capacity of N-oxidized metabolites of 4,4'-methylenebis(2-chloroaniline) (MBOCA) to form hemoglobin (Hb) adducts was determined in vitro, and the formation of Hb adducts following in vivo administration of MBOCA was...
6.
Kuslikis B, Trosko J, Braselton Jr W
Mutagenesis . 1991 Jan; 6(1):19-24. PMID: 2038268
Oxidized metabolites of 4,4'-methylenebis(2-chloroaniline) (MBOCA) were tested for direct mutagenicity in a Salmonella typhimurium assay and for effects on gap-junctional communication of WB-F344 rat liver cells. The mutagenicities of the...
7.
Vanden Heuvel J, Kuslikis B, Van Rafelghem M, Peterson R
J Biochem Toxicol . 1991 Jan; 6(2):83-92. PMID: 1941903
The elimination, tissue distribution, and metabolism of [1-14C]perfluorooctanoic acid (PFOA) was examined in male and female rats for 28 days after a single ip dose (9.4 mumol/kg, 4 mg/kg). A...
8.
Chen T, Kuslikis B, Braselton Jr W
Drug Metab Dispos . 1989 Jul; 17(4):406-13. PMID: 2571481
An in vitro microsomal mixed function oxidase enzyme system was used to study the phase I metabolism of 4,4'-methylenebis(2-chloroaniline) (MBOCA) by dog, guinea pig, and rat liver. TLC with color...
9.
Bruner C, Kuslikis B, Fink G
J Cardiovasc Pharmacol . 1987 Mar; 9(3):298-304. PMID: 2437396
The present experiments were designed to elucidate the role of central angiotensin II (AII) mechanisms in maintenance of established hypertension in adult spontaneously hypertensive rats (SHR) by determining the blood...