B G Kearns
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Explore the profile of B G Kearns including associated specialties, affiliations and a list of published articles.
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10
Citations
460
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Recent Articles
1.
Tsao Y, Cardoso A, Condon R, Voloch M, Lio P, Lagos J, et al.
J Biotechnol
. 2005 Jul;
118(3):316-27.
PMID: 16019100
Monitoring cell growth is crucial to the success of an animal cell culture process that can be accomplished by a variety of direct or indirect methodologies. Glucose is a major...
2.
Randazzo P, Miura K, Nie Z, Orr A, Theibert A, Kearns B
Trends Biochem Sci
. 2001 Apr;
26(4):220-1.
PMID: 11295547
No abstract available.
3.
Jackson T, Kearns B, Theibert A
Trends Biochem Sci
. 2000 Oct;
25(10):489-95.
PMID: 11050434
Receptor-activated phosphoinositide (PI) 3-kinases produce PtdIns(3, 4,5)P(3) and its metabolite PtdIns(3,4)P(2) that function as second messengers in membrane recruitment and activation of target proteins. The cytohesin and centaurin protein families...
4.
Nemoto Y, Kearns B, Wenk M, Chen H, Mori K, Alb Jr J, et al.
J Biol Chem
. 2000 Jul;
275(44):34293-305.
PMID: 10887188
The Saccharomyces cerevisiae SAC1 gene was identified via independent analyses of mutations that modulate yeast actin function and alleviate the essential requirement for phosphatidylinositol transfer protein (Sec14p) activity in Golgi...
5.
Rivas M, Kearns B, Xie Z, Guo S, Sekar M, Hosaka K, et al.
Mol Biol Cell
. 1999 Jul;
10(7):2235-50.
PMID: 10397762
SacIp dysfunction results in bypass of the requirement for phosphatidylinositol transfer protein (Sec14p) function in yeast Golgi processes. This effect is accompanied by alterations in inositol phospholipid metabolism and inositol...
6.
Kochendorfer K, Then A, Kearns B, Bankaitis V, Mayinger P
EMBO J
. 1999 Mar;
18(6):1506-15.
PMID: 10075922
Analysis of microsomal ATP transport in yeast resulted in the identification of Sac1p as an important factor in efficient ATP uptake into the endoplasmic reticulum (ER) lumen. Yet it remained...
7.
Kearns B, Alb Jr J, Bankaitis V
Trends Cell Biol
. 1998 Aug;
8(7):276-82.
PMID: 9714599
Phosphatidylinositol transfer proteins (PITPs) have historically been thought to help execute lipid-sorting events by transporting phospholipid monomers between membrane bilayers. Recent data, however, indicate unanticipated roles for PITPs in the...
8.
Kearns B, McGee T, Mayinger P, Gedvilaite A, Phillips S, Kagiwada S, et al.
Nature
. 1997 May;
387(6628):101-5.
PMID: 9139830
Yeast phosphatidylinositol transfer protein (Sec14p) is required for the production of secretory vesicles from the Golgi. This requirement can be relieved by inactivation of the cytosine 5'-diphosphate (CDP)-choline pathway for...
9.
Fang M, Kearns B, Gedvilaite A, Kagiwada S, Kearns M, Fung M, et al.
EMBO J
. 1996 Dec;
15(23):6447-59.
PMID: 8978672
The yeast phosphatidylinositol transfer protein (Sec14p) is required for biogenesis of Golgi-derived transport vesicles and cell viability, and this essential Sec14p requirement is abrogated by inactivation of the CDP-choline pathway...
10.
Kagiwada S, Kearns B, McGee T, Fang M, Hosaka K, Bankaitis V
Genetics
. 1996 Jun;
143(2):685-97.
PMID: 8725219
The BSD2-1 allele renders Saccharomyces cerevisiae independent of its normally essential requirement for phosphatidylinositol transfer protein (Sec14p) in the stimulation of Golgi secretory function and cell viability. We now report...