B G Hudson
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Explore the profile of B G Hudson including associated specialties, affiliations and a list of published articles.
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121
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2090
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Recent Articles
1.
Vanacore R, Pedchenko V, Bhave G, Hudson B
Clin Exp Immunol
. 2011 Mar;
164 Suppl 1:4-6.
PMID: 21447121
The sulphilimine cross-link of the Goodpasture (GP) autoantigen is a novel molecular mechanism (structural constraint) for conferring immune privilege to a site which otherwise is susceptible to structural changes that...
2.
Zent R, Yan X, Su Y, Hudson B, Borza D, Moeckel G, et al.
Kidney Int
. 2006 Jun;
70(3):460-70.
PMID: 16775606
Excessive glomerular collagen IV and reactive oxygen species (ROS) production are key factors in the development of diabetic nephropathy. Integrin alpha1beta1, the major collagen IV receptor, dowregulates collagen IV and...
3.
Voziyan P, Hudson B
Cell Mol Life Sci
. 2005 May;
62(15):1671-81.
PMID: 15905958
The discovery that pyridoxamine (PM) can inhibit glycation reactions and the formation of advanced glycation end products (AGEs) stimulated new interest in this B6 vitamer as a prospective pharmacological agent...
4.
Borza D, Bondar O, Ninomiya Y, Sado Y, Naito I, Todd P, et al.
J Biol Chem
. 2001 May;
276(30):28532-40.
PMID: 11375996
Type IV collagen, the major component of basement membranes (BMs), is a family of six homologous chains (alpha1-alpha6) that have a tissue-specific distribution. The chains assemble into supramolecular networks that...
5.
David M, Borza D, Leinonen A, Belmont J, Hudson B
J Biol Chem
. 2000 Dec;
276(9):6370-7.
PMID: 11098057
Goodpasture (GP) autoimmune disease is caused by autoantibodies to type IV collagen that bind to the glomerular basement membrane, causing rapidly progressing glomerulonephritis. The immunodominant GP(A) autoepitope is encompassed by...
6.
Boutaud A, Borza D, Bondar O, Gunwar S, Netzer K, Singh N, et al.
J Biol Chem
. 2000 Jul;
275(39):30716-24.
PMID: 10896941
The ultrafiltration function of the glomerular basement membrane (GBM) of the kidney is impaired in genetic and acquired diseases that affect type IV collagen. The GBM is composed of five...
7.
Ghohestani R, Hudson B, Claudy A, Uitto J
J Biol Chem
. 2000 May;
275(21):16002-6.
PMID: 10821854
We describe a novel autoimmune disease characterized by severe subepidermal bullous eruptions and renal insufficiency with IgG autoantibodies directed against the NC1 domain of the alpha5(IV) collagen chain. In vivo...
8.
Petitclerc E, Boutaud A, Prestayko A, Xu J, Sado Y, Ninomiya Y, et al.
J Biol Chem
. 2000 Mar;
275(11):8051-61.
PMID: 10713126
Collagen type IV is a major component of the basal lamina of blood vessels. Six genetically distinct collagen type IV chains have been identified and are distributed in a tissue-specific...
9.
Borza D, Netzer K, Leinonen A, Todd P, Cervera J, Saus J, et al.
J Biol Chem
. 2000 Feb;
275(8):6030-7.
PMID: 10681598
Goodpasture (GP) disease is an autoimmune disorder in which autoantibodies against the alpha3(IV) chain of type IV collagen bind to the glomerular and alveolar basement membranes, causing progressive glomerulonephritis and...
10.
Fervenza F, Terreros D, Boutaud A, Hudson B, Williams Jr R, Donadio Jr J, et al.
Am J Kidney Dis
. 1999 Sep;
34(3):549-55.
PMID: 10469867
We describe the case of a 54-year-old man who first presented with a clinical syndrome manifested by recurrent pulmonary hemorrhage, hematuria, and mild renal insufficiency. Direct immunofluorescence of renal biopsy...