B D Obermeyer
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Explore the profile of B D Obermeyer including associated specialties, affiliations and a list of published articles.
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12
Citations
54
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Recent Articles
1.
Brooks S, Lachno D, Obermeyer B
J Chromatogr B Biomed Sci Appl
. 1997 Apr;
691(2):383-8.
PMID: 9174275
A rapid and sensitive high-performance liquid chromatographic method for the determination of the novel ergoline derivatives sergolexole (compound I), its acid metabolite (compound II) and cis-n-(2-hydroxycyclopentyl)-6-methyl-1-(1-methylethyl)ergoline-8- carboxamide (LY215840, compound III)...
2.
Obermeyer B, Bergstrom R, Callaghan J, Knadler M, Golichowski A, Rubin A
Clin Pharmacol Ther
. 1990 Jun;
47(6):724-30.
PMID: 1972674
Disposition of the H2-receptor antagonist nizatidine was studied in serum, urine, and breast milk. Five lactating women and five nonlactating women participated; the disposition of nizatidine was studied in three...
3.
Schneck D, Callaghan J, Bergstrom R, Obermeyer B, Offen W
Clin Pharmacol Ther
. 1990 Apr;
47(4):499-503.
PMID: 2109665
Steady-state plasma nizatidine concentrations were related in a linear fashion to nizatidine infusion rate. Infusion rates of 2.5, 10, and 20 mg/hr resulted in mean plasma nizatidine concentrations of 69,...
4.
Knadler M, Bergstrom R, Callaghan J, Obermeyer B, Rubin A
Clin Pharmacol Ther
. 1987 Nov;
42(5):514-20.
PMID: 2890459
The absolute and relative bioavailability of nizatidine, an H2-blocker, was studied in healthy male volunteers. The absolute oral bioavailability, relative to that after intravenous administration, was 98% +/- 14%. The...
5.
Aronoff G, Wolen R, Obermeyer B, Black H
J Infect Dis
. 1986 Jun;
153(6):1069-74.
PMID: 3701118
The 1-methyl-1 H-tetrazole-5-thiol (MTT) side chain present on several new cephalosporins may be an important factor in coagulopathy observed during therapy with these antibiotics. To determine the plasma kinetics and...
6.
Callaghan J, Bergstrom R, Obermeyer B, King E, Offen W
Clin Pharmacol Ther
. 1985 Feb;
37(2):162-5.
PMID: 2857117
The effectiveness of intravenous nizatidine in suppressing gastric acid secretion was evaluated by different methods of inducing secretion in two single-blind studies. In study 1, seven subjects were given single,...
7.
DIVEN W, Obermeyer B, Wolen R, Yu V, Lyon J, Zuravleff J
Ther Drug Monit
. 1981 Jan;
3(3):291-5.
PMID: 6459665
We describe a sensitive high pressure liquid chromatographic (HPLC) procedure for the analysis of the new beta-lactam antibiotic moxalactam. Conditions are described for either measurement of total drug concentration or...
8.
Black H, Israel K, Wolen R, Brier G, Obermeyer B, Ziege E, et al.
Antimicrob Agents Chemother
. 1979 Feb;
15(2):165-70.
PMID: 426511
Cinoxacin was almost completely absorbed when given orally and was found to be approximately 60 to 70% protein bound. Peak serum concentrations were reached within 2 h, and detectable serum...
9.
Rubin A, Lemberger L, Dhahir P, Warrick P, CRABTREE R, Obermeyer B, et al.
Clin Pharmacol Ther
. 1978 Mar;
23(3):272-80.
PMID: 627132
Lergotrile, an ergot alkaloid, has been shown to be effective in treating disorders associated with elevated serum prolactin levels (e.g., galactorrhea-amenorrhea). Lergotrile has also been found to be a potent...
10.
Rubin A, Lemberger L, Warrick P, CRABTREE R, Sullivan H, Rowe H, et al.
Clin Pharmacol Ther
. 1977 Jul;
22(1):85-91.
PMID: 872500
Nabilone is a cannabinoid that is being evaluated in man as a potentially useful psychoactive drug. We found that nabilone was readily absorbed from the human gastrointestinal tract when administered...