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B Ardelt

Explore the profile of B Ardelt including associated specialties, affiliations and a list of published articles. Areas
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Articles 20
Citations 305
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Recent Articles
1.
Traganos F, Knuttihotz J, Hotz M, Gorczyca W, Ardelt B, Darzynkiewicz Z
Int J Oncol . 2011 May; 2(1):47-59. PMID: 21573514
The isoquinoline sulfonamide (H7) is an inhibitor of protein kinase C (PKC) that also inhibits the activity of cyclic nucleotide-dependent protein kinases. The effect of H7 on mitogen stimulation (G0...
2.
Gorczyca W, Ardelt B, Darzynkiewicz Z
Int J Oncol . 2011 May; 3(4):627-34. PMID: 21573410
One of the early events of apoptosis is proteolysis. The enzyme(s) involved in this event appear to be the serine protease(s), inasmuch as the reversible or irreversible inhibitors of serine...
3.
Halicka H, Ardelt B, Juan G, Mittelman A, Chen S, Traganos F, et al.
Int J Oncol . 2011 Apr; 11(3):437-48. PMID: 21528230
A herbal preparation denoted PC SPES(R) is available in 'natural food' or 'health food' stores in the United States. This mixture (patent pending, US Serial number 08/697,920) consists of extracts...
4.
Ardelt B, Juan G, Burfeind P, Salomon T, Wu J, Hsieh T, et al.
Int J Oncol . 2007 Aug; 31(3):663-9. PMID: 17671695
Onconase (ONC), an antitumor ribonuclease from oocytes of a frog Rana pipiens, capable of inducing apoptosis in many cell lines is synergistic with several other anticancer drugs. Since cytotoxic effects...
5.
Tsai S, Hsieh T, Ardelt B, Darzynkiewicz Z, Wu J
Int J Oncol . 2002 Apr; 20(5):891-6. PMID: 11956580
Prostate cancer (CaP), the most common malignancy in American men, presents its greatest challenge to clinicians when the cancer progresses to the hormone-refractory state. In the present investigation, we studied...
6.
Gorczyca W, Smolewski P, Grabarek J, Ardelt B, Ita M, Melamed M, et al.
Cytometry . 2001 Dec; 45(3):206-13. PMID: 11746089
Background: Various attributes of nucleoli, including abundance of the nucleolar product (rRNA), correlate with cell-proliferative status and are useful markers for tumor diagnosis and prognosis. However, there is a paucity...
7.
Ardelt B, Kunicki J, Traganos F, Darzynkiewicz Z
Int J Oncol . 2001 Mar; 18(4):849-53. PMID: 11251184
Chlorophyllin (CHL), the sodium and copper salt of chlorophyll, is capable of inhibiting the mutagenic activity of many chemical compounds. Several mechanisms have been advanced to explain the antimutagenic activity...
8.
Juan G, Ardelt B, Li X, Mikulski S, Shogen K, Ardelt W, et al.
Leukemia . 1998 Aug; 12(8):1241-8. PMID: 9697879
Onconase is a 12 kDa protein homologous to pancreatic RNase A isolated from amphibian oocytes which shows cytostatic and cytotoxic activity in vitro, inhibits growth of tumors in mice and...
9.
Deptala A, Halicka H, Ardelt B, Ardelt W, Mikulski S, Shogen K, et al.
Int J Oncol . 1998 Jun; 13(1):11-6. PMID: 9625797
Onconase (ONC) a ribonuclease from amphibian oocytes is cytostatic and cytotoxic to many human tumor lines, shows in vivo antitumor activity in mouse tumor models and is in Phase III...
10.
Kanthasamy A, Ardelt B, Malave A, Mills E, Powley T, Borowitz J, et al.
Toxicol Lett . 1998 Feb; 93(1):47-54. PMID: 9381482
Peroxide formation has been implicated in impairment of motor function by cyanide which occurs in both animals and man. The present study employs the neuronal model, rat pheochromocytoma (PC12) cells...