Aytekin Akyol
Overview
Explore the profile of Aytekin Akyol including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
821
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0
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Recent Articles
1.
Uzun S, Ozcan O, Gok A, Isik A, Bakir S, Gunel-Ozcan A, et al.
Animal Model Exp Med
. 2025 Feb;
PMID: 39956793
Adenomatous polyposis coli (APC) mutations are the most frequently identified genetic alteration in sporadic colorectal cancer (CRC) cases, and a myriad of genetically engineered Apc-mutant CRC mouse models have been...
2.
Gulec Taskiran A, Husnugil H, Soltani Z, Oral G, Menemenli N, Hampel C, et al.
Traffic
. 2024 Sep;
25(9):e12956.
PMID: 39313937
Limited nutrient availability in the tumor microenvironment can cause the rewiring of signaling and metabolic networks to confer cancer cells with survival advantages. We show here that the limitation of...
3.
Ozcan O, Akyol O, Akyol A
In Vivo
. 2024 Aug;
38(5):2300-2309.
PMID: 39187313
Background/aim: Inflammatory bowel diseases and colorectal cancer are a major cause of morbidity and mortality. Amine oxidase, copper-containing 3 (AOC3) is a critical enzyme in the physiological trafficking of leukocytes...
4.
Menemenli N, Ozcan O, Husnugil H, Gulec Taskiran A, Oral G, Akyol A, et al.
Methods Mol Biol
. 2024 Aug;
2879:93-111.
PMID: 39120739
During avian development, the chorioallantoic membrane (CAM) is generated around 4 days after fertilization following the fusion of the allantois and the chorion. The CAM develops rapidly over the next...
5.
Saatci O, Alam R, Huynh-Dam K, Isik A, Uner M, Belder N, et al.
Cell Death Dis
. 2024 Jun;
15(6):418.
PMID: 38879508
Tamoxifen has been the mainstay therapy to treat early, locally advanced, and metastatic estrogen receptor-positive (ER + ) breast cancer, constituting around 75% of all cases. However, the emergence of...
6.
Saatci O, Alam R, Huynh-Dam K, Isik A, Uner M, Belder N, et al.
bioRxiv
. 2024 Mar;
PMID: 38496603
Tamoxifen has been the mainstay therapy to treat early, locally advanced, and metastatic estrogen receptor-positive (ER+) breast cancer, constituting around 75% of all cases. However, emergence of resistance is common,...
7.
Husnugil H, Gulec Taskiran A, Guderer I, Nehri L, Oral G, Menemenli N, et al.
Transl Oncol
. 2024 Jan;
41:101860.
PMID: 38262111
Introduction: Nutrient restriction in cancer cells can activate a number of stress response pathways for cell survival. We aimed to determine mechanistically how nutrient depletion in colorectal cancer (CRC) cells...
8.
Saatci O, Cetin M, Uner M, Tokat U, Chatzistamou I, Ersan P, et al.
Nat Commun
. 2023 Nov;
14(1):6997.
PMID: 37914699
Resistance to endocrine therapy and CDK4/6 inhibitors, the standard of care (SOC) in estrogen receptor-positive (ER+) breast cancer, greatly reduces patient survival. Therefore, elucidating the mechanisms of sensitivity and resistance...
9.
Cerci B, Gok A, Akyol A
Cytokine Growth Factor Rev
. 2023 Jul;
71-72:105-116.
PMID: 37500391
Brain-derived neurotrophic factor (BDNF) plays an important role in the development of the central and peripheral nervous system during embryogenesis. In the mature central nervous system, BDNF is required for...
10.
Gok A, Isik A, Bakir S, Uzun S, Guner G, Ozcan O, et al.
In Vivo
. 2023 Jun;
37(4):1562-1575.
PMID: 37369509
Background/aim: Brain-derived neurotrophic factor (BDNF) is a growth factor of the neurotrophin family. Recent studies indicate that its expression is regulated by Wnt/β-catenin signaling. In this study, we aimed to...