Aymeric Chartier
Overview
Explore the profile of Aymeric Chartier including associated specialties, affiliations and a list of published articles.
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20
Citations
580
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Recent Articles
1.
Rojas-Rios P, Chartier A, Enjolras C, Cremaschi J, Garret C, Boughlita A, et al.
Nat Commun
. 2024 Sep;
15(1):8405.
PMID: 39333531
Stem cells preferentially use glycolysis instead of oxidative phosphorylation and this metabolic rewiring plays an instructive role in their fate; however, the underlying molecular mechanisms remain largely unexplored. PIWI-interacting RNAs...
2.
Nait-Saidi R, Chartier A, Abgueguen E, Guedat P, Simonelig M
Open Biol
. 2023 Apr;
13(4):230008.
PMID: 37042114
Oculopharyngeal muscular dystrophy (OPMD) is an autosomal dominant disease characterized by the progressive degeneration of specific muscles. OPMD is due to a mutation in the gene encoding poly(A) binding protein...
3.
Guenole A, Velilla F, Chartier A, Rich A, Carvunis A, Sardet C, et al.
Sci Rep
. 2022 Jun;
12(1):9288.
PMID: 35660762
Post-transcriptional regulatory mechanisms play a role in many biological contexts through the control of mRNA degradation, translation and localization. Here, we show that the RING finger protein RNF219 co-purifies with...
4.
Ribot C, Soler C, Chartier A, Al Hayek S, Nait-Saidi R, Barbezier N, et al.
PLoS Genet
. 2022 Jan;
18(1):e1010015.
PMID: 35025870
Oculopharyngeal muscular dystrophy (OPMD) is a late-onset disorder characterized by progressive weakness and degeneration of specific muscles. OPMD is due to extension of a polyalanine tract in poly(A) binding protein...
5.
Ramat A, Garcia-Silva M, Jahan C, Nait-Saidi R, Dufourt J, Garret C, et al.
Cell Res
. 2020 Mar;
30(5):421-435.
PMID: 32132673
Piwi-interacting RNAs (piRNAs) and PIWI proteins are essential in germ cells to repress transposons and regulate mRNAs. In Drosophila, piRNAs bound to the PIWI protein Aubergine (Aub) are transferred maternally...
6.
Dufourt J, Bontonou G, Chartier A, Jahan C, Meunier A, Pierson S, et al.
Nat Commun
. 2017 Nov;
8(1):1305.
PMID: 29101389
Piwi-interacting RNAs (piRNAs) and PIWI proteins play a crucial role in germ cells by repressing transposable elements and regulating gene expression. In Drosophila, maternal piRNAs are loaded into the embryo...
7.
Rojas-Rios P, Chartier A, Pierson S, Simonelig M
EMBO J
. 2017 Oct;
36(21):3194-3211.
PMID: 29030484
PIWI proteins play essential roles in germ cells and stem cell lineages. In , Piwi is required in somatic niche cells and germline stem cells (GSCs) to support GSC self-renewal...
8.
Chartier A, Joly W, Simonelig M
Methods Mol Biol
. 2016 Oct;
1463:93-102.
PMID: 27734350
mRNA regulation by poly(A) tail length variations plays an important role in many developmental processes. Recent advances have shown that, in particular, deadenylation (the shortening of mRNA poly(A) tails) is...
9.
Rojas-Rios P, Chartier A, Pierson S, Severac D, Dantec C, Busseau I, et al.
Dev Cell
. 2015 Dec;
35(5):622-631.
PMID: 26625957
Drosophila Orb, the homolog of vertebrate CPEB, is a key translational regulator involved in oocyte polarity and maturation through poly(A) tail elongation of specific mRNAs. orb also has an essential...
10.
Chartier A, Klein P, Pierson S, Barbezier N, Gidaro T, Casas F, et al.
PLoS Genet
. 2015 Mar;
11(3):e1005092.
PMID: 25816335
Oculopharyngeal muscular dystrophy (OPMD), a late-onset disorder characterized by progressive degeneration of specific muscles, results from the extension of a polyalanine tract in poly(A) binding protein nuclear 1 (PABPN1). While...