Axelle Loriot
Overview
Explore the profile of Axelle Loriot including associated specialties, affiliations and a list of published articles.
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39
Citations
688
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Recent Articles
1.
Beyaert S, Loriot A, Machiels J, Schmitz S
Int J Mol Sci
. 2025 Mar;
26(5).
PMID: 40076457
Afatinib-induced tumor and microenvironment modifications in head and neck squamous cell carcinoma were evaluated by spatial transcriptomics in surgical specimens and RNA-sequencing in tumor biopsies of patients included in the...
2.
Thibaut M, Roumain M, Piron E, Gillard J, Loriot A, Neyrinck A, et al.
Gut Microbes
. 2025 Jan;
17(1):2449586.
PMID: 39780051
Alterations in bile acid profile and pathways contribute to hepatic inflammation in cancer cachexia, a syndrome worsening the prognosis of cancer patients. As the gut microbiota impinges on host metabolism...
3.
Dvorakova T, Finisguerra V, Formenti M, Loriot A, Boudhan L, Zhu J, et al.
Nat Commun
. 2024 Sep;
15(1):7789.
PMID: 39242595
While adoptive cell therapy has shown success in hematological malignancies, its potential against solid tumors is hindered by an immunosuppressive tumor microenvironment (TME). In recent years, members of the hypoxia-inducible...
4.
Pirenne S, Manzano-Nunez F, Loriot A, Cordi S, Desmet L, Aydin S, et al.
BMC Cancer
. 2024 Aug;
24(1):1025.
PMID: 39164619
Background: Most studies on tumour progression from precursor lesion toward gallbladder adenocarcinoma investigate lesions sampled from distinct patients, providing an overarching view of pathogenic cascades. Whether this reflects the tumourigenic...
5.
Fain J, Wangermez C, Loriot A, Denoue C, De Smet C
Epigenomes
. 2024 Jul;
8(3).
PMID: 39051182
Human tumors progress in part by accumulating epigenetic alterations, which include gains and losses of DNA methylation in different parts of the cancer cell genome. Recent work has revealed a...
6.
Triaille C, Tilman G, Baert C, Sokolova T, Loriot A, Nzeusseu-Toukap A, et al.
Arthritis Rheumatol
. 2024 May;
76(9):1439-1445.
PMID: 38782587
Objective: The objective is to characterize transcriptomic profiles and immune cell composition and distribution in juvenile idiopathic arthritis (JIA) synovial biopsies, assess for associations of these features with clinical parameters,...
7.
Gratpain V, Loriot A, Bottemanne P, dAuria L, Terrasi R, Payen V, et al.
Heliyon
. 2024 Mar;
10(5):e27025.
PMID: 38463764
Neuro-inflammation occurs in numerous disorders such as multiple sclerosis, Alzheimer's disease and Parkinson's disease. However, anti-inflammatory drugs for the central nervous system have failed to show significant improvement when compared...
8.
Triaille C, Tilman G, Sokolova T, Loriot A, Marchandise J, De Montjoye S, et al.
Ann Rheum Dis
. 2023 Jul;
82(12):1538-1546.
PMID: 37507201
Objectives: Transcriptomic profiling of synovial tissue from patients with early, untreated rheumatoid arthritis (RA) was used to explore the ability of unbiased, data-driven approaches to define clinically relevant subgroups. Methods:...
9.
Gannoun L, De Schrevel C, Belle M, Dauguet N, Achouri Y, Loriot A, et al.
Development
. 2023 Jul;
150(16).
PMID: 37497580
Earlier data on liver development demonstrated that morphogenesis of the bile duct, portal mesenchyme and hepatic artery is interdependent, yet how this interdependency is orchestrated remains unknown. Here, using 2D...
10.
Gut microbiome modulates tacrolimus pharmacokinetics through the transcriptional regulation of ABCB1
Degraeve A, Haufroid V, Loriot A, Gatto L, Andries V, Vereecke L, et al.
Microbiome
. 2023 Jul;
11(1):138.
PMID: 37408070
Background: Following solid organ transplantation, tacrolimus (TAC) is an essential drug in the immunosuppressive strategy. Its use constitutes a challenge due to its narrow therapeutic index and its high inter-...