Axel Sauerbrey
Overview
Explore the profile of Axel Sauerbrey including associated specialties, affiliations and a list of published articles.
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33
Citations
1397
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Recent Articles
21.
Efferth T, Gebhart E, Ross D, Sauerbrey A
Biochem Pharmacol
. 2003 Aug;
66(4):613-21.
PMID: 12906926
The methylthioadenosine phosphorylase (MTAP) gene gained considerable interest as therapeutic target for tumors with the 9p21 deletion. This gene maps to 9p21 and loss of this chromosomal region in tumors...
22.
Efferth T, Sauerbrey A, Olbrich A, Gebhart E, Rauch P, Weber H, et al.
Mol Pharmacol
. 2003 Jul;
64(2):382-94.
PMID: 12869643
A profound cytotoxic action of the antimalarial, artesunate (ART), was identified against 55 cancer cell lines of the U.S. National Cancer Institute (NCI). The 50% inhibition concentrations (IC50 values) for...
23.
Efferth T, Sauerbrey A, Steinbach D, Gebhart E, Drexler H, Miyachi H, et al.
Int J Oncol
. 2003 Jul;
23(2):509-17.
PMID: 12851703
Multidrug resistance is an important mechanism responsible for refractoriness of leukemia and worse outcome of patients. Overexpression of the multidrug resistance gene, MDR1, is of prognostic relevance in acute myeloid...
24.
Steinbach D, Wittig S, Cario G, Viehmann S, Mueller A, Gruhn B, et al.
Blood
. 2003 Jun;
102(13):4493-8.
PMID: 12816874
The family of multidrug resistance-associated proteins (MRPs) belongs to the superfamily of adenosine triphosphate-binding-cassette (ABC) transporters, which have the ability to function as outward pumps for chemotherapeutic drugs and therefore...
25.
Hempel L, Sauerbrey A, Zintl F, Weirich A, Lemmer A, Graf N
Med Pediatr Oncol
. 2003 May;
41(1):97-9.
PMID: 12764765
No abstract available.
26.
Steinbach D, Lengemann J, Voigt A, Hermann J, Zintl F, Sauerbrey A
Clin Cancer Res
. 2003 Mar;
9(3):1083-6.
PMID: 12631611
Purpose: The family of multidrug resistance-associated proteins (MRPs) belongs to the ATP-binding cassette superfamily of transporters, which have the ability to function as outward pumps for chemotherapeutic drugs. Their structure,...
27.
Efferth T, Sauerbrey A, Halatsch M, Ross D, Gebhart E
Naunyn Schmiedebergs Arch Pharmacol
. 2003 Mar;
367(1):56-67.
PMID: 12616342
Homoharringtonine (HHT) is an ester of cephalotaxine (CET), both of which derive from the Chinese coniferous tree Cephalotaxus hainanensis. HHT inhibited tumor cell growth at molar ranges comparable to established...
28.
Efferth T, Olbrich A, Sauerbrey A, Ross D, Gebhart E, Neugebauer M
Anticancer Res
. 2003 Jan;
22(6C):4221-4.
PMID: 12553060
Ascaridol is the active principle of the American wormseed Chenopodium anthelminticum L. We isolated ascaridol from a commercial preparation of Chenopodium oil and analyzed its activity against different tumor cell...
29.
Efferth T, Verdorfer I, Miyachi H, Sauerbrey A, Drexler H, Chitambar C, et al.
Blood Cells Mol Dis
. 2002 Dec;
29(1):1-13.
PMID: 12482398
Ten T-cell acute lymphoblastic (T-ALL) CEM cell lines selected for resistance toward methotrexate (CEM/MTX60PGA, CEM/MTX140LV, CEM/MTX1500LV, CEM/MTX5000PGA, CEM/MTXR1, CEM/MTXR2, and CEM/MTXR3), doxorubicin (CEM/ADR5000), vincristine (CEM/VCR1000), or hydroxyurea (CEM/HUR90), respectively, and...
30.
Mentzel H, Kentouche K, Kosmehl H, Gruhn B, Vogt S, Sauerbrey A, et al.
Pediatr Radiol
. 2002 Aug;
32(3):195-8.
PMID: 12164354
Abdominal problems often complicate the clinical course after bone marrow transplantation. Graft-versus-host disease occurs as a complication of allogenic bone marrow transplantation. In this report, the findings of intestinal involvement...