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Axel Sauerbrey

Explore the profile of Axel Sauerbrey including associated specialties, affiliations and a list of published articles. Areas
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Articles 33
Citations 1397
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Recent Articles
1.
Sonksen M, Obrecht-Sturm D, Hernaiz Driever P, Sauerbrey A, Graf N, Kontny U, et al.
Neuro Oncol . 2024 Jun; 26(11):2125-2139. PMID: 38919026
Background: The outcome of children with medulloblastoma (MB) and Fanconi Anemia (FA), an inherited DNA repair deficiency, has not been described systematically. Treatment is complicated by high vulnerability to treatment-associated...
2.
Dohna M, Renz D, Stehling F, Dohna-Schwake C, Sutharsan S, Neurohr C, et al.
BMJ Open Respir Res . 2021 Aug; 8(1). PMID: 34385150
Introduction: Massive haemoptysis is a life-threatening event in advanced cystic fibrosis (CF) lung disease with bronchial artery embolisation (BAE) as standard of care treatment. The aim of our study was...
3.
Stanulla M, Schaeffeler E, Moricke A, Buchmann S, Zimmermann M, Igel S, et al.
Leukemia . 2021 Mar; 35(9):2650-2657. PMID: 33714975
Long-term treatment with 6-thioguanine (6-TG) for pediatric acute lymphoblastic leukemia (ALL) is associated with high rates of hepatic sinusoidal obstruction syndrome (SOS). Nevertheless, current treatment continues to use short-term applications...
4.
Roick J, Berner R, Bernig T, Erdlenbruch B, Escherich G, Faber J, et al.
BMC Pediatr . 2020 Feb; 20(1):48. PMID: 32005112
Background: About 2000 children and adolescents under the age of 18 are diagnosed with cancer each year in Germany. Because of current medical treatment methods, a high survival rate can...
5.
Desch A, Hartung K, Botzen A, Brobeil A, Rummel M, Kurch L, et al.
Leukemia . 2019 Aug; 34(1):151-166. PMID: 31431735
We used hybrid capture-targeted next-generation sequencing of circulating cell-free DNA (ccfDNA) of pediatric Hodgkin lymphoma (PHL) patients to determine pathogenic mechanisms and assess the clinical utility of this method. Hodgkin-Reed/Sternberg...
6.
Kewitz-Hempel S, Kurch L, Cepelova M, Volkmer I, Sauerbrey A, Conrad E, et al.
Mol Imaging Biol . 2019 Apr; 21(6):1182-1191. PMID: 30945122
Purpose: The enzyme O6-methylguanine-DNA methyltransferase (MGMT) is an important component of the DNA repair machinery. MGMT removes O6-methylguanine from the DNA by transferring the methyl group to a cysteine residue...
7.
Greiner J, Schrappe M, Claviez A, Zimmermann M, Niemeyer C, Kolb R, et al.
Haematologica . 2018 Sep; 104(4):756-765. PMID: 30262570
Thromboembolism is a serious complication of induction therapy for childhood acute lymphoblastic leukemia. We prospectively compared the efficacy and safety of antithrombotic interventions in the consecutive leukemia trials ALL-BFM 2000...
8.
Krumbholz A, Neubert A, Joel S, Girschick H, Huppertz H, Kaiser P, et al.
Pediatr Infect Dis J . 2013 Oct; 33(3):258-62. PMID: 24168981
Background: Since asymptomatic hepatitis E virus (HEV) infections particularly affect children, there is a need for studies to determine the HEV seroprevalence among infants, children and adolescents. Methods: The prevalence...
9.
Kotlarz D, Beier R, Murugan D, Diestelhorst J, Jensen O, Boztug K, et al.
Gastroenterology . 2012 May; 143(2):347-55. PMID: 22549091
Background & Aims: Homozygous loss of function mutations in interleukin-10 (IL10) and interleukin-10 receptors (IL10R) cause severe infantile (very early onset) inflammatory bowel disease (IBD). Allogeneic hematopoietic stem cell transplantation...
10.
von Kries R, Weiss S, Falkenhorst G, Wirth S, Kaiser P, Huppertz H, et al.
PLoS One . 2011 Sep; 6(9):e23955. PMID: 21915270
Background: We determined antibodies to the pandemic influenza A (H1N1) 2009 virus in children to assess: the incidence of (H1N1) 2009 infections in the 2009/2010 season in Germany, the proportion...