Axel Hage
Overview
Explore the profile of Axel Hage including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
33
Followers
0
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Recent Articles
1.
Schneider A, Hage A, Stein I, Kriedemann N, Zweigerdt R, Leffler A
Int J Mol Sci
. 2024 Jun;
25(12).
PMID: 38928302
An accumulation of reactive oxygen species (ROS) in cardiomyocytes can induce pro-arrhythmogenic late Na currents by removing the inactivation of voltage-gated Na channels including the tetrodotoxin (TTX)-resistant cardiac α-subunit Nav1.5...
2.
Haug F, Pumroy R, Sridhar A, Pantke S, Dimek F, Fricke T, et al.
EMBO J
. 2024 Apr;
43(11):2264-2290.
PMID: 38671253
Transient receptor potential (TRP) ion channels are involved in the surveillance or regulation of the acid-base balance. Here, we demonstrate that weak carbonic acids, including acetic acid, lactic acid, and...
3.
Hage A, de Vries M, Leffler A, Stoetzer C
J Exp Pharmacol
. 2022 Nov;
14:353-365.
PMID: 36385942
Introduction: Chloroquine (CQ) and its derivate hydroxychloroquine (HCQ) are successfully deployed for different diseases beyond the prophylaxis and treatment of malaria. Both substances exhibit antiviral properties and have been proposed...
4.
Poffers M, Buhne N, Herzog C, Thorenz A, Chen R, Guler F, et al.
Anesthesiology
. 2018 Mar;
128(6):1151-1166.
PMID: 29509584
Background: Voltage-gated sodium channels generate action potentials in excitable cells, but they have also been attributed noncanonical roles in nonexcitable cells. We hypothesize that voltage-gated sodium channels play a functional...
5.
Stueber T, Meyer S, Jangra A, Hage A, Eberhardt M, Leffler A
Life Sci
. 2017 Dec;
194:67-74.
PMID: 29273526
Aims: The anandamide reuptake inhibitor N-arachidonoylaminophenol (AM404) and the reactive substance N-acetyl-p-benzoquinone imine (NAPQI) are both metabolites of acetaminophen and may contribute to acetaminophen-induced analgesia by acting at TRPV1 expressed...
6.
de la Roche J, Walther I, Leonow W, Hage A, Eberhardt M, Fischer M, et al.
Sci Rep
. 2016 Nov;
6:36740.
PMID: 27827430
Tissue ischemia results in an accumulation of lactate and local or systemic lactic acidosis. In nociceptive sensory neurons, lactate was reported to sensitize or activate the transient receptor potential ion...
7.
Vant Klooster M, Foadi N, Hage A, Stoetzer C, Wegner F, Eberhardt M, et al.
Eur J Pharmacol
. 2016 Jul;
789:119-126.
PMID: 27401036
5-hydroxytryptamine 3 receptor (5-HT3 receptor) antagonists are administered for prevention and therapy of nausea and vomiting. Although regarded as safe therapeutics, they can also provoke arrhythmias by prolonging the QRS...