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Awet Abraha

Explore the profile of Awet Abraha including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 783
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Recent Articles
1.
Nankya I, Tebit D, Abraha A, Kyeyune F, Gibson R, Jegede O, et al.
AIDS Res Ther . 2015 Oct; 12:34. PMID: 26435727
Background: CCR5-using (r5) HIV-1 predominates during asymptomatic disease followed by occasional emergence of CXCR4-using (x4) or dual tropic (r5x4) virus. We examined the contribution of the x4 and r5 components...
2.
Rubio A, Abraha A, Carpenter C, Troyer R, Reyes-Rodriguez A, Salomon H, et al.
PLoS One . 2014 Apr; 9(4):e92084. PMID: 24727861
The HIV-1 epidemic in South America is dominated by pure subtypes (mostly B and C) and more than 7 BF and BC recombinant forms. In Argentina, circulating recombinant forms (CRFs)...
3.
Gao Y, Abreha M, Nelson K, Baird H, Dudley D, Abraha A, et al.
Retrovirology . 2011 Jan; 8(1):5. PMID: 21232148
Background: Intersubtype HIV-1 recombinants in the form of unique or stable circulating recombinants forms (CRFs) are responsible for over 20% of infections in the worldwide epidemic. Mechanisms controlling the generation,...
4.
Troyer R, McNevin J, Liu Y, Zhang S, Krizan R, Abraha A, et al.
PLoS Pathog . 2009 Apr; 5(4):e1000365. PMID: 19343217
Human lymphocyte antigen (HLA)-restricted CD8(+) cytotoxic T lymphocytes (CTL) target and kill HIV-infected cells expressing cognate viral epitopes. This response selects for escape mutations within CTL epitopes that can diminish...
5.
Abraha A, Nankya I, Gibson R, Demers K, Tebit D, Johnston E, et al.
J Virol . 2009 Mar; 83(11):5592-605. PMID: 19297481
Human immunodeficiency virus type 1 (HIV-1) subtype C is the dominant subtype globally, due largely to the incidence of subtype C infections in sub-Saharan Africa and east Asia. We compared...
6.
Gao Y, Nankya I, Abraha A, Troyer R, Nelson K, Rubio A, et al.
Methods Mol Biol . 2008 Nov; 485:27-35. PMID: 19020816
Studies of HIV-1 replication kinetics and fitness require an accurate determination of the level of infectious HIV-1 present in virus stocks. The standard technique for measuring the level of replication-competent...
7.
Gao Y, Lobritz M, Roth J, Abreha M, Nelson K, Nankya I, et al.
J Virol . 2008 Jan; 82(6):2938-51. PMID: 18199654
Small interfering RNAs (siRNAs) have been shown to effectively inhibit human immunodeficiency virus type 1 (HIV-1) replication in vitro. The mechanism(s) for this inhibition is poorly understood, as siRNAs may...
8.
Ndembi N, Abraha A, Pilch H, Ichimura H, Mbanya D, Kaptue L, et al.
J Clin Microbiol . 2007 Sep; 46(1):177-84. PMID: 17855574
Prior to current studies on the emergence of drug resistance with the introduction of antiretroviral therapy (ART) in Cameroon, we performed genotypic analysis on samples from drug-naïve, human immunodeficiency virus...
9.
Abraha A, Troyer R, Quinones-Mateu M, Arts E
Methods Mol Biol . 2005 Aug; 304:355-68. PMID: 16061989
The fitness of human immunodeficiency virus type-1 (HIV-1) appears to be an important piece of the puzzle in understanding the global HIV-1 epidemic and disease progression in infected individuals. We...
10.
Troyer R, Collins K, Abraha A, Fraundorf E, Moore D, Krizan R, et al.
J Virol . 2005 Jul; 79(14):9006-18. PMID: 15994794
This study examined the relationship between ex vivo human immunodeficiency virus type 1 (HIV-1) fitness and viral genetic diversity during the course of HIV-1 disease. Primary HIV-1 isolates from 10...