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Avram J Holmes

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Articles 118
Citations 8407
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Recent Articles
1.
Orchard E, Chopra S, Ooi L, Chen P, An L, Jamadar S, et al.
Proc Natl Acad Sci U S A . 2025 Feb; 122(9):e2411245122. PMID: 39999172
The experience of human parenthood is near ubiquitous and can profoundly alter one's body, mind, and environment. However, we know very little about the long-term neural effects of parenthood for...
2.
Ricard J, Labache L, Segal A, Dhamala E, Cocuzza C, Jones G, et al.
Commun Biol . 2025 Feb; 8(1):293. PMID: 39988590
No abstract available.
3.
Dhamala E, Ricard J, Uddin L, Galea L, Jacobs E, Yip S, et al.
Nat Neurosci . 2024 Dec; 28(2):222-233. PMID: 39730766
Considerable heterogeneity exists in the expression of complex human behaviors across the cognitive, personality and mental health domains. It is increasingly evident that individual variability in behavioral expression is substantially...
4.
Zhang X, Anderson K, Dong H, Chopra S, Dhamala E, Emani P, et al.
Nat Neurosci . 2024 Nov; 28(1):150-160. PMID: 39572742
The functional properties of the human brain arise, in part, from the vast assortment of cell types that pattern the cerebral cortex. The cortical sheet can be broadly divided into...
5.
Segal A, Tiego J, Parkes L, Holmes A, Marquand A, Fornito A
Trends Cogn Sci . 2024 Nov; 29(1):85-99. PMID: 39510933
Despite decades of research, we lack objective diagnostic or prognostic biomarkers of mental health problems. A key reason for this limited progress is a reliance on the traditional case-control paradigm,...
6.
Chopra S, Dhamala E, Lawhead C, Ricard J, Orchard E, An L, et al.
Sci Adv . 2024 Nov; 10(45):eadn1862. PMID: 39504381
A primary aim of computational psychiatry is to establish predictive models linking individual differences in brain functioning with symptoms. In particular, cognitive impairments are transdiagnostic, treatment resistant, and associated with...
7.
Qu Y, Chopra S, Qu S, Cocuzza C, Labache L, Bauer C, et al.
bioRxiv . 2024 Nov; PMID: 39484470
Background: Exposure to major life stressors and aberrant functional connectivity have been linked to anxiety and depression, especially during adolescence. However, whether specific characteristics of life stressors and functional network...
8.
Garcia-Marin L, Campos A, Diaz-Torres S, Rabinowitz J, Ceja Z, Mitchell B, et al.
Nat Genet . 2024 Oct; 56(11):2333-2344. PMID: 39433889
Subcortical brain structures are involved in developmental, psychiatric and neurological disorders. Here we performed genome-wide association studies meta-analyses of intracranial and nine subcortical brain volumes (brainstem, caudate nucleus, putamen, hippocampus,...
9.
Garcia-Marin L, Campos A, Diaz-Torres S, Rabinowitz J, Ceja Z, Mitchell B, et al.
medRxiv . 2024 Oct; PMID: 39371125
Subcortical brain structures are involved in developmental, psychiatric and neurological disorders. We performed GWAS meta-analyses of intracranial and nine subcortical brain volumes (brainstem, caudate nucleus, putamen, hippocampus, globus pallidus, thalamus,...
10.
Ricard J, Labache L, Segal A, Dhamala E, Cocuzza C, Jones G, et al.
Commun Biol . 2024 Sep; 7(1):1178. PMID: 39300138
The biological mechanisms that contribute to cocaine and other substance use disorders involve an array of cortical and subcortical systems. Prior work on the development and maintenance of substance use...