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Ava J Y Guo

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Articles 14
Citations 263
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Recent Articles
1.
Chen J, Li Z, Zheng K, Guo A, Zhu K, Zhang W, et al.
Acta Pharm . 2014 Jan; 63(4):505-15. PMID: 24451075
Gleditsiae Fructus Abnormalis and Gleditsiae Sinensis Fructus are obtained from different developmental stages of fruits from Gleditsia sinensis Lam. (Leguminosae). The possible interchangeable usage of the two fruits, however, has...
2.
Choi R, Zhu J, Yung A, Lee P, Xu S, Guo A, et al.
Evid Based Complement Alternat Med . 2013 Sep; 2013:635694. PMID: 24058373
Despite the classical hormonal effect, estrogen has been reported to mediate neuroprotection in the brain, which leads to the searching of estrogen-like substances for treating neurodegenerative diseases. Flavonoids, a group...
3.
Xu S, Choi R, Zhu K, Leung K, Guo A, Bi D, et al.
Evid Based Complement Alternat Med . 2012 Jul; 2012:278273. PMID: 22761636
Flavonoids, a group of compounds mainly derived from vegetables and herbal medicines, share a chemical resemblance to estrogen, and indeed some of which have been used as estrogen substitutes. In...
4.
Chen V, Luk W, Chan W, Leung K, Guo A, Chan G, et al.
Front Mol Neurosci . 2011 Nov; 4:36. PMID: 22046147
Acetylcholinesterase (AChE) is responsible for the hydrolysis of the neurotransmitter, acetylcholine, in the nervous system. The functional localization and oligomerization of AChE T variant are depending primarily on the association...
5.
Chen V, Choi R, Chan W, Leung K, Guo A, Chan G, et al.
J Biol Chem . 2011 Jul; 286(38):32948-61. PMID: 21795704
Acetylcholinesterase (AChE) anchors onto cell membranes by a transmembrane protein PRiMA (proline-rich membrane anchor) as a tetrameric form in vertebrate brain. The assembly of AChE tetramer with PRiMA requires the...
6.
Guo A, Choi R, Cheung A, Chen V, Xu S, Dong T, et al.
J Biol Chem . 2011 Jun; 286(32):27882-93. PMID: 21652696
Flavonoids, a group of natural compounds found in a variety of vegetables and herbal medicines, have been intensively reported on regarding their estrogen-like activities and particularly their ability to affect...
7.
Zheng K, Choi R, Cheung A, Guo A, Bi C, Zhu K, et al.
J Agric Food Chem . 2011 Feb; 59(5):1697-704. PMID: 21309574
Radix Astragali (RA) is commonly used as a health food supplement to reinforce the body vital energy. Flavonoids, including formononetin, ononin, calycosin, and calycosin-7-O-β-d-glucoside, are considered to be the major...
8.
Zheng K, Choi R, Xie H, Cheung A, Guo A, Leung K, et al.
J Ethnopharmacol . 2010 Aug; 132(1):259-67. PMID: 20723591
Ethnopharmacological Evidence: Danggui buxue tang (DBT), a Chinese medicinal decoction that is being commonly used as hematopoietic medicine to treating woman menopausal irregularity, contains two herbs: radix Astragali and radix...
9.
Guo A, Xie H, Choi R, Zheng K, Bi C, Xu S, et al.
Chem Biol Interact . 2010 May; 187(1-3):246-8. PMID: 20452337
Acetylcholinesterase (AChE) inhibitors are widely used for the treatment of Alzheimer's disease (AD). Several AChE inhibitors, e.g. rivastigmine, galantamine and huperzine are originating from plants, suggesting that herbs could potentially...
10.
Xie H, Leung K, Chen V, Chan G, Xu S, Guo A, et al.
Chem Biol Interact . 2010 Feb; 187(1-3):78-83. PMID: 20178777
Acetylcholinesterase (AChE), a highly polymorphic enzyme with various splicing variants and molecular isoforms, plays an essential role in the cholinergic neurotransmission by hydrolyzing acetylcholine into choline and acetate. The AChE(T)...