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Aurelien Thomas

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Articles 102
Citations 1391
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Recent Articles
1.
Laghezza A, Falbo E, Gilardi F, Thomas A, Brunetti L, Leuci R, et al.
Eur J Med Chem . 2025 Mar; 289:117494. PMID: 40088662
A rational drug design approach led to the synthesis of three pairs of enantiomers derived from the peroxisome proliferator-activated receptor (PPAR) pan agonist AL29-26, identifying (S)-2 as a potent and...
2.
Xie S, Perrais M, Golshayan D, Wuerzner G, Vaucher J, Thomas A, et al.
Clin Kidney J . 2025 Feb; 18(2):sfae378. PMID: 39950154
Background: Chronic kidney disease (CKD) is an important public health problem. Although cross-sectional studies have identified many heavy metals/trace elements associated with reduced kidney function, prospective studies are needed to...
3.
Maret E, Wiskott K, Shipley T, Gilardi F, Augsburger M, Thomas A, et al.
Proteomics Clin Appl . 2024 Dec; 19(2):e202400022. PMID: 39704561
Purpose: Traumatic brain injury (TBI), including pediatric abusive head trauma (AHT), is the leading cause of death and disability in children and young adults worldwide. The current understanding of trauma-induced...
4.
Mouti I, Perrais M, Marques-Vidal P, Thomas A, Vaucher J
Sci Rep . 2024 Nov; 14(1):29725. PMID: 39614087
The ToxiLaus study aims at evaluating the impact of environmental toxic species on health and diseases' onset and development. Specifically, the ubiquitous presence of trace elements (TEs) in the environment...
5.
Igloi K, Marin Bosch B, Kuenzi N, Thomas A, Lauer E, Bringard A, et al.
Cereb Cortex . 2024 May; 34(5. PMID: 38802684
The ε4 allele of the APOE gene heightens the risk of late onset Alzheimer's disease. ε4 carriers, may exhibit cognitive and neural changes early on. Given the known memory-enhancing effects...
6.
Perrais M, Trachsel B, Lenglet S, Pruijm M, Ponte B, Vogt B, et al.
Clin Chem Lab Med . 2024 Apr; 62(11):2242-2255. PMID: 38641868
Objectives: Trace elements (TEs) are ubiquitous. TE concentrations vary among individuals and countries, depending on factors such as living area, workplaces and diet. Deficit or excessive TEs concentrations have consequences...
7.
Frias M, Pagano S, Bararpour N, Sidibe J, Kamau F, Fetaud-Lapierre V, et al.
Front Cardiovasc Med . 2024 Feb; 11:1343361. PMID: 38414919
Objective: This study aimed to study the relationship between auto-antibodies against apolipoprotein A1 (anti-apoA1 IgG), human immunodeficiency virus (HIV) infection, anti-retroviral therapy (ART), and the tryptophan pathways in HIV-related cardiovascular...
8.
Sajic T, Ferreira Gomes C, Gasser M, Caputo T, Bararpour N, Landaluce-Iturriria E, et al.
Int J Obes (Lond) . 2023 Dec; 48(4):557-566. PMID: 38148333
Background: In obesity, adipose tissue undergoes a remodeling process characterized by increased adipocyte size (hypertrophia) and number (hyperplasia). The ability to tip the balance toward the hyperplastic growth, with recruitment...
9.
de La Harpe R, Schoeler T, Thorball C, Thomas A, Kutalik Z, Vaucher J
BMC Cardiovasc Disord . 2023 Dec; 23(1):611. PMID: 38093188
Background: Association between cannabis use and development of atherosclerotic cardiovascular disease (ASCVD) is inconsistent and challenging to interpret, given existing study limitations. Methods: Sixty five independent single-nucleotide polymorphisms (SNPs), obtained...
10.
Ghobril J, Petrovic D, Ehret G, Ponte B, Pruijm M, Ackermann D, et al.
Chimia (Aarau) . 2023 Dec; 76(12):1052-1062. PMID: 38069802
The recent advent of high-throughput sequencing technologies has allowed exploring the contribution of thousands of genomic, epigenomic, transcriptomic, or proteomic variants to complex phenotypic traits. Here, we sought to conduct...