Audrey Bernut
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Explore the profile of Audrey Bernut including associated specialties, affiliations and a list of published articles.
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28
Citations
1073
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Recent Articles
1.
Weimann A, Dinan A, Ruis C, Bernut A, Pont S, Brown K, et al.
Science
. 2024 Jul;
385(6704):eadi0908.
PMID: 38963857
The major human bacterial pathogen causes multidrug-resistant infections in people with underlying immunodeficiencies or structural lung diseases such as cystic fibrosis (CF). We show that a few environmental isolates, driven...
2.
Le Moigne V, Rodriguez Rincon D, Glatigny S, Dupont C, Langevin C, Ait Ali Said A, et al.
Am J Respir Cell Mol Biol
. 2022 Jan;
66(4):439-451.
PMID: 35081328
Persistent neutrophilic inflammation associated with chronic pulmonary infection causes progressive lung injury and, eventually, death in individuals with cystic fibrosis (CF), a genetic disease caused by biallelic mutations in the...
3.
Bernut A, Loynes C, Floto R, Renshaw S
Front Immunol
. 2020 Aug;
11:1733.
PMID: 32849617
Inflammation-related progressive lung destruction is the leading causes of premature death in cystic fibrosis (CF), a genetic disorder caused by a defective cystic fibrosis transmembrane conductance regulator (CFTR). However, therapeutic...
4.
Batalha I, Bernut A, Schiebler M, Ouberai M, Passemar C, Klapholz C, et al.
J Control Release
. 2019 Oct;
314:116-124.
PMID: 31647980
Mycobacterium tuberculosis (Mtb) remains a major challenge to global health, made worse by the spread of multi-drug resistance. Currently, the efficacy and safety of treatment is limited by difficulties in...
5.
Le Moigne V, Bernut A, Cortes M, Viljoen A, Dupont C, Pawlik A, et al.
Front Microbiol
. 2019 May;
10:905.
PMID: 31114557
, a pathogen responsible for severe lung infections in cystic fibrosis patients, exhibits either smooth (S) or rough (R) morphotypes. The S-to-R transition correlates with inhibition of the synthesis and/or...
6.
Bernut A, Dupont C, Ogryzko N, Neyret A, Herrmann J, Floto R, et al.
Cell Rep
. 2019 Feb;
26(7):1828-1840.e4.
PMID: 30759393
Infection by rapidly growing Mycobacterium abscessus is increasingly prevalent in cystic fibrosis (CF), a genetic disease caused by a defective CF transmembrane conductance regulator (CFTR). However, the potential link between...
7.
Dubois V, Viljoen A, Laencina L, Le Moigne V, Bernut A, Dubar F, et al.
Proc Natl Acad Sci U S A
. 2018 Oct;
115(43):E10147-E10156.
PMID: 30301802
is a peculiar rapid-growing (RGM) capable of surviving within eukaryotic cells thanks to an arsenal of virulence genes also found in slow-growing mycobacteria (SGM), such as A screen based on...
8.
Malcolm K, Caceres S, Pohl K, Poch K, Bernut A, Kremer L, et al.
PLoS One
. 2018 Apr;
13(4):e0196120.
PMID: 29672589
Mycobacterium abscessus, a rapidly growing nontuberculous mycobacterium, are increasingly present in soft tissue infections and chronic lung diseases, including cystic fibrosis, and infections are characterized by growth in neutrophil-rich environments....
9.
Laencina L, Dubois V, Le Moigne V, Viljoen A, Majlessi L, Pritchard J, et al.
Proc Natl Acad Sci U S A
. 2018 Jan;
115(5):E1002-E1011.
PMID: 29343644
, a rapidly growing mycobacterium (RGM) and an opportunistic human pathogen, is responsible for a wide spectrum of clinical manifestations ranging from pulmonary to skin and soft tissue infections. This...
10.
Bernut A, Herrmann J, Ordway D, Kremer L
Front Cell Infect Microbiol
. 2017 Apr;
7:100.
PMID: 28421165
represents an important respiratory pathogen among the rapidly-growing non-tuberculous mycobacteria. Infections caused by are increasingly found in cystic fibrosis (CF) patients and are often refractory to antibiotic therapy. The underlying...