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Audree Laroche

Explore the profile of Audree Laroche including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 197
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Recent Articles
1.
Schultz I, Dos Santos Pereira Andrade A, Dubuc I, Laroche A, Allaeys I, Dore E, et al.
Stem Cell Rev Rep . 2024 Sep; 21(2):564-580. PMID: 39340739
The Coronavirus Disease 2019 (COVID-19), caused by virus SARS-CoV-2, is characterized by massive inflammation and immune system imbalance. Despite the implementation of vaccination protocols, the accessibility of treatment remains uneven....
2.
Carrier M, Robert M, St-Pierre M, Gonzalez Ibanez F, de Andrade E, Laroche A, et al.
iScience . 2024 Jul; 27(7):110037. PMID: 39021809
Although the roles of embryonic yolk sac-derived, resident microglia in neurodevelopment were extensively studied, the possible involvement of bone marrow-derived cells remains elusive. In this work, we used a fate-mapping...
3.
Puhm F, Laroche A, Boilard E
Arterioscler Thromb Vasc Biol . 2023 Sep; 43(11):2088-2098. PMID: 37675634
Megakaryocytes are commonly known as large, polyploid, bone marrow resident cells that contribute to hemostasis through the production of platelets. Soon after their discovery in the 19th century, megakaryocytes were...
4.
Laroche A, Soulet D, Bazin M, Levesque T, Allaeys I, Vallieres N, et al.
Blood Adv . 2022 Apr; 6(12):3697-3702. PMID: 35452514
Immune complexes form in systemic disorders such as rheumatological, autoimmune, and allergic diseases or in response to infections or medications. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) adenoviral vector vaccines...
5.
Marcoux G, Laroche A, Hasse S, Bellio M, Mbarik M, Tamagne M, et al.
Blood . 2021 Jul; 138(25):2607-2620. PMID: 34293122
In addition to their hemostatic role, platelets play a significant role in immunity. Once activated, platelets release extracellular vesicles (EVs) formed by the budding of their cytoplasmic membranes. Because of...
6.
Melki I, Allaeys I, Tessandier N, Levesque T, Cloutier N, Laroche A, et al.
Sci Transl Med . 2021 Feb; 13(581). PMID: 33597264
The accumulation of DNA and nuclear components in blood and their recognition by autoantibodies play a central role in the pathophysiology of systemic lupus erythematosus (SLE). Despite the efforts, the...
7.
Melki I, Allaeys I, Tessandier N, Mailhot B, Cloutier N, Campbell R, et al.
Blood . 2020 Dec; 136(25):2933-2945. PMID: 33331924
Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease characterized by deposits of immune complexes (ICs) in organs and tissues. The expression of FcγRIIA by human platelets, which is their...
8.
French S, Butov K, Allaeys I, Canas J, Morad G, Davenport P, et al.
Blood Adv . 2020 Jul; 4(13):3011-3023. PMID: 32614966
During inflammation, steady-state hematopoiesis switches to emergency hematopoiesis to repopulate myeloid cells, with a bias toward the megakaryocytic lineage. Soluble inflammatory cues are thought to be largely responsible for these...
9.
Marcoux G, Laroche A, Espinoza Romero J, Boilard E
Platelets . 2020 Jun; 32(3):340-351. PMID: 32597341
The immune system is comprised of two principal interconnected components called innate and adaptive immunity. While the innate immune system mounts a nonspecific response that provides protection against the spread...
10.
Marcoux G, Magron A, Sut C, Laroche A, Laradi S, Hamzeh-Cognasse H, et al.
Transfusion . 2019 Apr; 59(7):2403-2414. PMID: 30973972
Background: Whereas platelet transfusion is a common medical procedure, inflammation still occurs in a fraction of transfused individuals despite the absence of any apparent infectious agents. Platelets can shed membrane...