Athina Georgiadou
Overview
Explore the profile of Athina Georgiadou including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
258
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Recent Articles
1.
Dunican C, Andradi-Brown C, Ebmeier S, Georgiadou A, Cunnington A
Biochem Soc Trans
. 2024 Feb;
52(2):651-660.
PMID: 38421063
The blood transcriptome of malaria patients has been used extensively to elucidate the pathophysiological mechanisms and host immune responses to disease, identify candidate diagnostic and prognostic biomarkers, and reveal new...
2.
Najer A, Blight J, Ducker C, Gasbarri M, Brown J, Che J, et al.
ACS Cent Sci
. 2022 Oct;
8(9):1238-1257.
PMID: 36188342
Infectious diseases continue to pose a substantial burden on global populations, requiring innovative broad-spectrum prophylactic and treatment alternatives. Here, we have designed modular synthetic polymer nanoparticles that mimic functional components...
3.
Georgiadou A, Dunican C, Soro-Barrio P, Lee H, Kaforou M, Cunnington A
Elife
. 2022 Jan;
11.
PMID: 35006075
Recent initiatives to improve translation of findings from animal models to human disease have focussed on reproducibility but quantifying the relevance of animal models remains a challenge. Here, we use...
4.
Georgiadou A, Naidu P, Walsh S, Kamiza S, Barrera V, Harding S, et al.
Clin Transl Immunology
. 2021 May;
10(4):e1263.
PMID: 33968402
Objective: Cerebral malaria (CM) is a complication of malaria, in which progressive brain swelling is associated with sequestration of parasites and impaired barrier function of the cerebral microvascular endothelium. To...
5.
Katsoulis O, Georgiadou A, Cunnington A
Front Immunol
. 2021 May;
12:651739.
PMID: 33968051
Acute kidney injury (AKI) is a common feature of severe malaria, and an independent risk factor for death. Previous research has suggested that an overactivation of the host inflammatory response...
6.
Knackstedt S, Georgiadou A, Apel F, Abu-Abed U, Moxon C, Cunnington A, et al.
Sci Immunol
. 2019 Oct;
4(40).
PMID: 31628160
Neutrophils are essential innate immune cells that extrude chromatin in the form of neutrophil extracellular traps (NETs) when they die. This form of cell death has potent immunostimulatory activity. We...
7.
Georgiadou A, Lee H, Walther M, van Beek A, Fitriani F, Wouters D, et al.
Nat Microbiol
. 2019 Jun;
4(9):1592-1602.
PMID: 31209307
During infection, increasing pathogen load stimulates both protective and harmful aspects of the host response. The dynamics of this interaction are hard to quantify in humans, but doing so could...
8.
Georgiadou A, Cunnington A
Clin Infect Dis
. 2019 Jan;
69(10):1721-1723.
PMID: 30698670
No abstract available.
9.
Tabrizi M, Lancaster T, Ismail T, Georgiadou A, Ganguly A, Mistry J, et al.
Sci Rep
. 2018 Aug;
8(1):11488.
PMID: 30065265
S100P has been shown to be a marker for carcinogenesis where its expression in solid tumours correlates with metastasis and a poor patient prognosis. This protein's role in any physiological...
10.
Lee H, Georgiadou A, Walther M, Nwakanma D, Stewart L, Levin M, et al.
Sci Transl Med
. 2018 Jun;
10(447).
PMID: 29950443
The pathogenesis of infectious diseases depends on the interaction of host and pathogen. In malaria, host and parasite processes can be assessed by dual RNA sequencing of blood from infected...