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Athanasios S Alexandris

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Citations 72
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Recent Articles
1.
Alexandris A, Rafaels K, Horsmon M, Wozniak S, Belamarich J, Flores P, et al.
J Neurotrauma . 2024 Dec; PMID: 39723444
Traumatic brain injury (TBI) after high-energy, behind helmet blunt trauma (BHBT) is an important but poorly understood clinical entity often associated with apnea and death in humans. In this study,...
2.
Alexandris A, Koliatsos V
Antioxid Redox Signal . 2023 Jul; 39(16-18):1167-1184. PMID: 37503611
The remarkable geometry of the axon exposes it to unique challenges for survival and maintenance. Axonal degeneration is a feature of peripheral neuropathies, glaucoma, and traumatic brain injury, and an...
3.
Alexandris A, Lee Y, Lehar M, Alam Z, McKenney J, Perdomo D, et al.
J Neurotrauma . 2023 Jan; 40(15-16):1743-1761. PMID: 36680758
Traumatic axonal injury (TAI), thought to be caused by rotational acceleration of the head, is a prevalent neuropathology in traumatic brain injury (TBI). TAI in the optic nerve is a...
4.
Alexandris A, Lee Y, Lehar M, Alam Z, Samineni P, Tripathi S, et al.
Exp Neurol . 2022 Oct; 359:114252. PMID: 36244414
Traumatic axonal injury (TAI) and the associated axonopathy are common consequences of traumatic brain injury (TBI) and contribute to significant neurological morbidity. It has been previously suggested that TAI activates...
5.
Alexandris A, Wang Y, Frangakis C, Lee Y, Ryu J, Alam Z, et al.
Int J Mol Sci . 2022 Jul; 23(13). PMID: 35806394
White matter pathology is common across a wide spectrum of neurological diseases. Characterizing this pathology is important for both a mechanistic understanding of neurological diseases as well as for the...
6.
Alexandris A, Ryu J, Rajbhandari L, Harlan R, McKenney J, Wang Y, et al.
Neurobiol Dis . 2022 Jul; 171:105808. PMID: 35779777
Wallerian degeneration (WD) is a conserved axonal self-destruction program implicated in several neurological diseases. WD is driven by the degradation of the NAD synthesizing enzyme NMNAT2, the buildup of its...
7.
Welsbie D, Ziogas N, Xu L, Kim B, Ge Y, Patel A, et al.
Mol Neurodegener . 2019 Nov; 14(1):44. PMID: 31775817
Background: Traumatic brain injury (TBI) is a major cause of CNS neurodegeneration and has no disease-altering therapies. It is commonly associated with a specific type of biomechanical disruption of the...
8.
Ryu J, Vincent P, Ziogas N, Xu L, Sadeghpour S, Curtin J, et al.
PLoS One . 2019 Nov; 14(11):e0224846. PMID: 31710637
Optogenetically engineered human neural progenitors (hNPs) are viewed as promising tools in regenerative neuroscience because they allow the testing of the ability of hNPs to integrate within nervous system of...
9.
Koliatsos V, Alexandris A
Curr Opin Neurol . 2019 Oct; 32(6):786-795. PMID: 31633494
Purpose Of Review: Diffuse or traumatic axonal injury is one of the principal pathologies encountered in traumatic brain injury (TBI) and the resulting axonal loss, disconnection, and brain atrophy contribute...