Astrid Wirtz
Overview
Explore the profile of Astrid Wirtz including associated specialties, affiliations and a list of published articles.
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24
Citations
241
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Recent Articles
1.
de Witt J, Luthe T, Wiechert J, Jensen K, Polen T, Wirtz A, et al.
Nat Microbiol
. 2025 Feb;
10(3):667-680.
PMID: 39929973
Aliphatic polyamides, or nylons, are widely used in the textile and automotive industry due to their high durability and tensile strength, but recycling rates are below 5%. Chemical recycling of...
2.
Ernst P, Zlati F, Kever L, Wirtz A, Goldbaum R, Pietruszka J, et al.
Metab Eng Commun
. 2024 Dec;
19:e00252.
PMID: 39655188
There is a strong interest in itaconic acid in the medical and pharmaceutical sectors, both as an anti-bacterial compound and as an immunoregulator in mammalian macrophages. Fungal hosts also produce...
3.
Ernst P, Wirtz A, Wynands B, Wierckx N
FEMS Yeast Res
. 2024 Jul;
24.
PMID: 39038994
Ustilago maydis and Ustilago cynodontis are natural producers of a broad range of valuable molecules including itaconate, malate, glycolipids, and triacylglycerols. Both Ustilago species are insensitive toward medium impurities, and...
4.
Ramp P, Mack C, Wirtz A, Bott M
Metab Eng
. 2023 May;
78:1-10.
PMID: 37146873
d-chiro-Inositol (DCI) is a promising drug candidate for treating insulin resistance and associated diseases such as type 2 diabetes or polycystic ovary syndrome. In this study, we developed two production...
5.
Zuchowski R, Schito S, Neuheuser F, Menke P, Berger D, Hollmann N, et al.
Microb Cell Fact
. 2023 Apr;
22(1):71.
PMID: 37061714
Background: Amino acid production features of Corynebacterium glutamicum were extensively studied in the last two decades. Many metabolic pathways, regulatory and transport principles are known, but purely rational approaches often...
6.
Stella R, Baumann P, Lorke S, Munstermann F, Wirtz A, Wiechert J, et al.
Metab Eng Commun
. 2021 Nov;
13:e00187.
PMID: 34824977
The marine bacterium has recently been demonstrated to be a promising new host for molecular biology and next generation bioprocesses. is a Gram-negative, non-pathogenic slight-halophilic bacterium, with a high nutrient...
7.
Wohlers K, Wirtz A, Reiter A, Oldiges M, Baumgart M, Bott M
Microb Biotechnol
. 2021 Aug;
14(6):2592-2604.
PMID: 34437751
5-Ketofructose (5-KF) is a promising low-calorie natural sweetener with the potential to reduce health problems caused by excessive sugar consumption. It is formed by periplasmic oxidation of fructose by fructose...
8.
Hage-Hulsmann J, Klaus O, Linke K, Troost K, Gora L, Hilgers F, et al.
J Biotechnol
. 2021 Jul;
338:20-30.
PMID: 34237394
Terpenes constitute one of the largest groups of secondary metabolites that are used, for example, as food-additives, fragrances or pharmaceuticals. Due to the formation of an intracytoplasmic membrane system and...
9.
Ramp P, Lehnert A, Matamouros S, Wirtz A, Baumgart M, Bott M
Metab Eng
. 2021 Jul;
67:173-185.
PMID: 34224896
Scyllo-inositol has been identified as a potential drug for the treatment of Alzheimer's disease. Therefore, cost-efficient processes for the production of this compound are desirable. In this study, we analyzed...
10.
Hunnefeld M, Viets U, Sharma V, Wirtz A, Hardy A, Frunzke J
Viruses
. 2021 Apr;
13(3).
PMID: 33802915
In this study, we provide a comprehensive analysis of the genomic features of the phage CL31 and the infection dynamics with the biotechnologically relevant host strain ATCC 13032. Genome sequencing...