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Astrid C Schauss

Explore the profile of Astrid C Schauss including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 1533
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Recent Articles
1.
Pla-Martin D, Babatz F, Schauss A
Methods Mol Biol . 2023 Feb; 2615:173-188. PMID: 36807792
Reminiscent of their evolutionary origin, mitochondria contain their own genome (mtDNA) compacted into the mitochondrial chromosome or nucleoid (mt-nucleoid). Many mitochondrial disorders are characterized by disruption of mt-nucleoids, either by...
2.
Sen A, Kallabis S, Gaedke F, Jungst C, Boix J, Nuchel J, et al.
Nat Commun . 2022 Nov; 13(1):6704. PMID: 36344526
Understanding the mechanisms governing selective turnover of mutation-bearing mtDNA is fundamental to design therapeutic strategies against mtDNA diseases. Here, we show that specific mtDNA damage leads to an exacerbated mtDNA...
3.
Lobastova L, Lettau M, Babatz F, de Oliveira T, Nguyen P, Pauletti B, et al.
Front Cell Dev Biol . 2021 Aug; 9:698503. PMID: 34395429
CD30, a member of the TNF receptor superfamily, is selectively expressed on a subset of activated lymphocytes and on malignant cells of certain lymphomas, such as classical Hodgkin Lymphoma (cHL),...
4.
Steinbach A, Cornely O, Wisplinghoff H, Schauss A, Vehreschild J, Rybniker J, et al.
Mycoses . 2019 Apr; 62(7):562-569. PMID: 31034691
Invasive mould infections (IMI) in immunocompromised patients are difficult to diagnose. Early and targeted treatment is paramount, but minimally invasive tests reliably identifying pathogens are lacking. We previously showed that...
5.
Bachurski D, Schuldner M, Nguyen P, Malz A, Reiners K, Grenzi P, et al.
J Extracell Vesicles . 2019 Apr; 8(1):1596016. PMID: 30988894
The expanding field of extracellular vesicle (EV) research needs reproducible and accurate methods to characterize single EVs. Nanoparticle Tracking Analysis (NTA) is commonly used to determine EV concentration and diameter....
6.
Gessner I, Yu X, Jungst C, Klimpel A, Wang L, Fischer T, et al.
Sci Rep . 2019 Feb; 9(1):2069. PMID: 30765836
MicroRNAs (miRNAs) are small non-coding nucleotides playing a crucial role in posttranscriptional expression and regulation of target genes in nearly all kinds of cells. In this study, we demonstrate a...
7.
Koehler F, Cornely O, Wisplinghoff H, Schauss A, Salmanton-Garcia J, Ostermann H, et al.
Front Microbiol . 2018 Jul; 9:1381. PMID: 29988394
Blood or tissue culture or histology prove invasive infection, but long time to result, limited feasibility and sensitivity call for new approaches. In this pilot project, we describe the diagnostic...
8.
Rubsam M, Mertz A, Kubo A, Marg S, Jungst C, Goranci-Buzhala G, et al.
Nat Commun . 2017 Nov; 8(1):1250. PMID: 29093447
Generation of a barrier in multi-layered epithelia like the epidermis requires restricted positioning of functional tight junctions (TJ) to the most suprabasal viable layer. This positioning necessitates tissue-level polarization of...
9.
Kohli P, Hohne M, Jungst C, Bertsch S, Ebert L, Schauss A, et al.
EMBO Rep . 2017 Jul; 18(9):1521-1535. PMID: 28710093
Primary cilia are sensory, antennae-like organelles present on the surface of many cell types. They have been involved in a variety of diseases collectively termed ciliopathies. As cilia are essential...
10.
Bultmann-Mellin I, Dinger K, Debuschewitz C, Loewe K, Melcher Y, Plum M, et al.
Am J Physiol Lung Cell Mol Physiol . 2017 Jul; 313(4):L687-L698. PMID: 28684544
Deficiency of the extracellular matrix protein latent transforming growth factor-β (TGF-β)-binding protein-4 (LTBP4) results in lack of intact elastic fibers, which leads to disturbed pulmonary development and lack of normal...